Akgün Y, Akşit F
Mikrobiyol Bul. 1981 Jul;15(2):112-20.
82 candida strains isolated from clinical material were tested for their sensitivity to nystatin, 5-fluorocytosine (5-FC) and to clotrimazole. Strains were showing high M.I.C. values against nystatin and 45% primary resistance to 5-FC by the tube dilution technique. No resistance was noted to clotrimazole. The resistance, developed in candida strains against several antifungal drugs, will establish the problem encountered in the antibiotic treatment of bacterial infections. Also the necessity of the sensitivity tests with the isolated candida strains in candida infections is emphasized.
对从临床材料中分离出的82株念珠菌菌株进行了制霉菌素、5-氟胞嘧啶（5-FC）和克霉唑敏感性测试。通过试管稀释技术，菌株对制霉菌素显示出高最低抑菌浓度（M.I.C.）值，对5-FC有45%的原发性耐药性。未发现对克霉唑耐药。念珠菌菌株对几种抗真菌药物产生的耐药性将引发在细菌感染抗生素治疗中遇到的问题。同时强调了对念珠菌感染中分离出的念珠菌菌株进行敏感性测试的必要性。
