Serpa Maria João, Franco Susana, Repolho Diana, Araújo Isabel, Mateus Sofia, Baptista António Martins, Araújo José Lomelino
Internal Medicine Department, Hospital Beatriz Ângelo, Lisbon, Portugal.
Eur J Case Rep Intern Med. 2018 Oct 24;5(10):000952. doi: 10.12890/2018_000952. eCollection 2018.
Ischaemic ulcers of the lower limb can have several aethiopathological mechanisms. For instance, the uncommon Martorell hypertensive leg ulcer is an infrequent complication of long-term uncontrolled arterial hypertension and is largely ignored and underdiagnosed. The typical ulcer is on the lower leg, is extremely painful and presents in female patients over 60 years of age with cardiovascular risk factors, mainly severe arterial hypertension. The diagnosis is histological, with obliteration of the arterioles by arteriolosclerosis. In these cases, antihypertensive medication is the standard treatment. We describe the case of an African-American female patient with long-term hypertension who presented with a very painful leg ulcer. The diagnosis was complicated by the coexistence of more common causes of ulcer. Despite analgesic medicines, pain relief was only obtained with control of hypertension. A definite diagnosis was made following biopsy. In describing this diagnosis of an ischaemic leg ulcer, we highlight the need to consider the skin as a target organ of arterial hypertension.
Martorell hypertensive leg ulcer is an underdiagnosed cutaneous lesion arising from long-term uncontrolled hypertension.The diagnosis is confirmed by histopathology.Standard treatment is adequate control of blood pressure.
下肢缺血性溃疡可有多种病因病理机制。例如,不常见的马托雷尔高血压性腿部溃疡是长期未控制的动脉高血压的罕见并发症,很大程度上被忽视且诊断不足。典型溃疡位于小腿,极为疼痛,见于60岁以上有心血管危险因素(主要是重度动脉高血压)的女性患者。诊断靠组织学检查,可见小动脉硬化导致小动脉闭塞。在这些病例中,抗高血压药物是标准治疗方法。我们描述了一名患有长期高血压的非裔美国女性患者出现非常疼痛的腿部溃疡的病例。由于同时存在更常见的溃疡病因,诊断变得复杂。尽管使用了镇痛药,但只有控制住高血压才能缓解疼痛。活检后做出了明确诊断。在描述这种缺血性腿部溃疡的诊断时,我们强调需要将皮肤视为动脉高血压的靶器官。
马托雷尔高血压性腿部溃疡是一种因长期未控制的高血压而诊断不足的皮肤病变。诊断通过组织病理学证实。标准治疗是充分控制血压。