Zão Inês, Ribeiro Fani, Rocha Valter, Neto Pedro, Matias Carla, Jesus Gorete
Internal Medicine Department, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal.
Intensive Care Department, Centro Hospitalar Entre Douro e Vouga, Santa Maria da Feira, Portugal.
Eur J Case Rep Intern Med. 2018 Nov 28;5(11):000977. doi: 10.12890/2018_000977. eCollection 2018.
(MP) is a common cause of respiratory infections and can be associated with extrapulmonary complications. MP mucositis has recently been described as a distinct endemic clinical entity called e-induced rash and mucositis (MIRM). The authors present the case of a 46-year-old man with atypical pneumonia associated with exuberant mucositis, conjunctival hyperaemia and positive serological assays for MP IgM. The patient was treated with azithromycin and systemic corticosteroid therapy. Supportive care including pain management, intravenous hydration and mucosal care was also given. There was complete resolution of the pneumonia and mucositis. The presence of atypical pneumonia with mucosal involvement without cutaneous lesions and a favourable clinical evolution led to the diagnosis of MIRM.
infection can be associated with mucocutaneous lesions. A new entity called -induced rash and mucositis (MIRM) has been recently described. The mucocutaneous involvement associated with MIRM is predominantly mucositis with scarce or absent cutaneous expression.The clinical presentation, pathophysiology and disease outcomes of MIRM distinguish it from Stevens-Johnson syndrome/toxic epidermal necrolysis and erythema multiform.MIRM has an overall favourable prognosis as the majority of patients recover without sequalae and recurrence is rare.
肺炎支原体（MP）是呼吸道感染的常见病因，可伴有肺外并发症。MP 黏膜炎最近被描述为一种独特的地方性临床实体，称为 e 诱导性皮疹和黏膜炎（MIRM）。作者报告了一例 46 岁男性患者，患有非典型肺炎，伴有严重黏膜炎、结膜充血，MP IgM 血清学检测呈阳性。患者接受了阿奇霉素和全身糖皮质激素治疗。还给予了包括疼痛管理、静脉补液和黏膜护理在内的支持性治疗。肺炎和黏膜炎完全消退。出现非典型肺炎伴黏膜受累但无皮肤病变且临床进展良好，从而诊断为 MIRM。
感染可伴有皮肤黏膜病变。最近描述了一种名为 e 诱导性皮疹和黏膜炎（MIRM）的新实体。与 MIRM 相关的皮肤黏膜受累主要为黏膜炎，皮肤表现稀少或无。MIRM 的临床表现、病理生理学和疾病转归使其有别于史蒂文斯 - 约翰逊综合征/中毒性表皮坏死松解症和多形红斑。MIRM 的总体预后良好，因为大多数患者康复后无后遗症，复发罕见。
