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一项针对澳大利亚 97852 名 45 岁及以上饮酒者戒酒相关健康状况的前瞻性研究。

A Prospective Study of Health Conditions Related to Alcohol Consumption Cessation Among 97,852 Drinkers Aged 45 and Over in Australia.

机构信息

Cancer Research Division , Cancer Council New South Wales, Kings Cross, New South Wales, Australia.

Sydney School of Public Health , The University of Sydney, Sydney, New South Wales, Australia.

出版信息

Alcohol Clin Exp Res. 2019 Apr;43(4):710-721. doi: 10.1111/acer.13981. Epub 2019 Mar 7.

DOI:10.1111/acer.13981
PMID:30758044
Abstract

BACKGROUND

Evidence suggests that people who develop serious health conditions are likely to cease drinking alcohol (sometimes known as "sick-quitters"). We quantified the likelihood of quitting drinking in relation to the onset of a variety of health conditions.

METHODS

Odds ratios (ORs) and 95% confidence intervals (CIs) of ceasing alcohol consumption after diagnosis of 28 health conditions and 4 general indicators of health were derived from logistic regression among 97,852 drinkers aged ≥ 45 years between baseline (2006 to 2009) and median 5.3 years of follow-up in the New South Wales 45 and Up Study. Incident health conditions at follow-up were self-reported.

RESULTS

At follow-up, 9.6% (n = 9,438) of drinkers had ceased drinking. Drinking cessation was significantly associated with 24 of 32 health conditions examined: 15.4% of participants with newly diagnosed diabetes quit drinking (OR for quitting vs. continuing 1.77, 95% CI: 1.60 to 1.96), 16.4% with Parkinson's disease (1.71, 1.35 to 2.17), 17.8% with poor memory (1.68, 1.43 to 1.97), 19.2% with hip fracture (1.64, 1.30 to 2.06), 14.7% with stroke (1.45, 1.27 to 1.66), 12.5% with depression (1.40, 1.26 to 1.55), 15.0% with breast cancer (1.38, 1.18 to 1.61), 12.3% with heart disease (1.34, 1.25 to 1.44), and 13.3% with osteoarthritis (1.22, 1.12 to 1.33). Strong associations with quitting were observed in those with a decline in self-rated overall health (2.93, 2.53 to 3.40) and quality of life (2.68, 2.24 to 3.21). Some health conditions not significantly associated with quitting were prostate cancer, melanoma, nonmelanoma skin cancer, hay fever, and hearing loss. Findings were generally consistent for men and women, by age group and by smoking status.

CONCLUSIONS

Diagnosis with a variety of health conditions appears to prompt drinking cessation in older adults.

摘要

背景

有证据表明,出现严重健康问题的人更有可能停止饮酒(有时称为“因病戒酒”)。我们量化了与各种健康状况相关的戒酒可能性。

方法

在新南威尔士州 45 岁及以上研究中,对 97852 名年龄在 45 岁及以上的饮酒者进行了基线(2006 年至 2009 年)和中位 5.3 年随访期间的 28 种健康状况和 4 种健康一般指标的诊断后,使用逻辑回归得出了停止饮酒的几率比(OR)和 95%置信区间(CI)。随访时的新发健康状况由自我报告。

结果

随访时,9.6%(n=9438)的饮酒者已经戒酒。饮酒停止与 32 种健康状况中的 24 种显著相关:新诊断为糖尿病的参与者中有 15.4%停止饮酒(与继续饮酒相比,戒酒的几率比为 1.77,95%CI:1.60 至 1.96),16.4%患有帕金森病(1.71,1.35 至 2.17),17.8%记忆力减退(1.68,1.43 至 1.97),19.2%髋部骨折(1.64,1.30 至 2.06),14.7%中风(1.45,1.27 至 1.66),12.5%抑郁症(1.40,1.26 至 1.55),15.0%乳腺癌(1.38,1.18 至 1.61),12.3%心脏病(1.34,1.25 至 1.44),13.3%骨关节炎(1.22,1.12 至 1.33)。与自我评估整体健康状况下降(2.93,2.53 至 3.40)和生活质量下降(2.68,2.24 至 3.21)相关的戒酒几率也很高。一些与戒酒无关的健康状况包括前列腺癌、黑色素瘤、非黑色素瘤皮肤癌、花粉热和听力损失。这些发现对于男性和女性、不同年龄组和吸烟状况基本一致。

结论

诊断出多种健康状况似乎会促使老年人戒酒。

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