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103年后,是时候从教科书中取消亨德森-哈塞尔巴尔赫方程了吗?

[After 103 years, is it time to cancel the Hasselbalch equation from textbooks?].

作者信息

Sgambato Francesco, Prozzo Sergio, Sgambato Ester

机构信息

U. O. C. di Medicina Interna - Ospedale Fatebenefratelli - Benevento.

U. O. C. Medicina e Chirurgia di Accettazione e Urgenza - Osp. S. Eugenio - Roma.

出版信息

G Ital Nefrol. 2019 Feb;36(1).

Abstract

The equation called "Henderson-Hasselbalch Equation" was created in 1916 following the Henderson Equation published in 1908. After analyzing the evolution from the simplicity of Henderson to the complexity of Hasselbalch, it is hoped that the acid-base balance can become a simpler and more exciting topic if approached and taught without using the Henderson-Hasselbalch equation, which includes 4 logarithms. It is stated that the rationale underlying the understanding of acid-base equilibrium and its clinical application is already clearly inherent in the much simpler Henderson formula (without logarithms), which is sufficient, and very useful, for both teaching and learning in Medicine.

摘要

名为“亨德森 - 哈塞尔巴尔赫方程”的等式是在1908年发表的亨德森方程之后于1916年创建的。在分析了从亨德森的简单形式到哈塞尔巴尔赫的复杂形式的演变之后,人们希望,如果在讲解和教授酸碱平衡时不使用包含4个对数的亨德森 - 哈塞尔巴尔赫方程,那么酸碱平衡可以成为一个更简单、更有趣的主题。有人指出,理解酸碱平衡及其临床应用的基本原理已经清晰地蕴含在简单得多的亨德森公式(不包含对数)中,这对于医学教学和学习来说已经足够且非常有用。

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