1型糖尿病患者自身抗体呈阳性的一级亲属中，循环miRNA-375水平升高。 - Suppr | 超能文献

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Circulating miRNA-375 levels are increased in autoantibodies-positive first-degree relatives of type 1 diabetes patients.1型糖尿病患者自身抗体呈阳性的一级亲属中，循环miRNA-375水平升高。

Acta Diabetol. 2019 Jun;56(6):707-710. doi: 10.1007/s00592-019-01297-7. Epub 2019 Feb 13.

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High prevalence of diabetes-specific autoimmunity in first-degree relatives of Sardinian patients with type 1 diabetes.撒丁岛1型糖尿病患者一级亲属中糖尿病特异性自身免疫的高患病率。

Diabetes Metab Res Rev. 2017 Mar;33(3). doi: 10.1002/dmrr.2864. Epub 2016 Nov 30.

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Association of serum microRNAs with islet autoimmunity, disease progression and metabolic impairment in relatives at risk of type 1 diabetes.血清微小RNA与1型糖尿病高危亲属的胰岛自身免疫、疾病进展及代谢损害的关联

Diabetologia. 2017 Aug;60(8):1409-1422. doi: 10.1007/s00125-017-4294-3. Epub 2017 May 12.

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Temporal dynamics of serum let-7g expression mirror the decline of residual beta-cell function in longitudinal observation of children with type 1 diabetes.血清 let-7g 表达的时间动态反映了 1 型糖尿病患儿纵向观察中剩余β细胞功能的下降。

Pediatr Diabetes. 2018 Dec;19(8):1407-1415. doi: 10.1111/pedi.12783. Epub 2018 Oct 12.

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The high prevalence of autoantibodies to tissue transglutaminase in first-degree relatives of patients with type 1 diabetes is not associated with islet autoimmunity.1型糖尿病患者一级亲属中组织转谷氨酰胺酶自身抗体的高患病率与胰岛自身免疫无关。

Diabetes Care. 2001 Mar;24(3):504-9. doi: 10.2337/diacare.24.3.504.

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Tetraspanin 7 autoantibodies in type 1 diabetes.1型糖尿病中的四跨膜蛋白7自身抗体。

Diabetologia. 2016 Sep;59(9):1973-6. doi: 10.1007/s00125-016-3997-1. Epub 2016 May 25.

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Comparative analysis of organ-specific autoantibodies and celiac disease--associated antibodies in type 1 diabetic patients, their first-degree relatives, and healthy control subjects.1型糖尿病患者、其一级亲属及健康对照者中器官特异性自身抗体与乳糜泻相关抗体的比较分析

Diabetes Care. 2001 Jan;24(1):27-32. doi: 10.2337/diacare.24.1.27.

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Only multiple autoantibodies to islet cells (ICA), insulin, GAD65, IA-2 and IA-2beta predict immune-mediated (Type 1) diabetes in relatives.只有针对胰岛细胞（ICA）、胰岛素、GAD65、IA-2和IA-2β的多种自身抗体才能预测亲属中免疫介导的（1型）糖尿病。

J Autoimmun. 1999 Jun;12(4):279-87. doi: 10.1006/jaut.1999.0281.

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Autoimmunity to the GM2-1 islet ganglioside before and at the onset of type I diabetes.在I型糖尿病发病前及发病时对GM2-1胰岛神经节苷脂的自身免疫反应。

Diabetes. 1996 Sep;45(9):1193-6. doi: 10.2337/diab.45.9.1193.

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Autoantibodies and human leucocyte antigen class II in first-degree family members of Mexican-American type 1 diabetic patients.墨西哥裔美国 1 型糖尿病患者一级家庭成员中的自身抗体与人类白细胞抗原 II 类分子

J Clin Endocrinol Metab. 2001 Oct;86(10):4957-62. doi: 10.1210/jcem.86.10.7944.

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MiR-375: it could be a general biomarker of metabolic changes and inflammation in type 1 diabetes patients and their siblings.微小RNA-375：它可能是1型糖尿病患者及其兄弟姐妹代谢变化和炎症的一种通用生物标志物。

J Endocrinol Invest. 2025 Mar;48(3):757-764. doi: 10.1007/s40618-024-02474-4. Epub 2024 Oct 25.

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A set of circulating microRNAs belonging to the 14q32 chromosome locus identifies two subgroups of individuals with recent-onset type 1 diabetes.一组属于 14q32 染色体位置的循环 microRNAs 可识别出近期发病的 1 型糖尿病个体的两个亚群。

Cell Rep Med. 2024 Jun 18;5(6):101591. doi: 10.1016/j.xcrm.2024.101591. Epub 2024 Jun 4.

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