在开始辅助治疗前，通过情绪功能来筛查乳腺癌和结直肠癌患者的心理困扰。
Emotional functioning to screen for psychological distress in breast and colorectal cancer patients prior to adjuvant treatment initiation.
机构信息
Department of Clinical Psychology and Psychobiology, Faculty of Psychology, University of Barcelona, Spain.
Department of Medical Oncology, Hospital Universitario Morales Meseguer, Murcia, Spain.
出版信息
Eur J Cancer Care (Engl). 2019 May;28(3):e13005. doi: 10.1111/ecc.13005. Epub 2019 Feb 13.
INTRODUCTION
The objective was to analyze the usefulness of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC-QLQ-C30) EF subscale to detect emotional problems in patients with breast (BC) and colorectal cancer (CRC).
METHODS
A prospective, observational, cross-sectional study was conducted. Participants completed the Brief Symptom Inventory (BSI) and EORTC-QLQ-C30. The following psychometric properties were calculated: accuracy, sensitivity, positive predictive value, specificity and negative predictive value.
RESULTS
The sample analyzed included 445 patients: 202 with BC and 243 with CRC. In total, 129 BC patients (64%) and 104 CRC patients (43%) suffered psychological distress according to the BSI. The accuracy of EORTC-QLQ-C30 EF in detecting psychological distress was 77% and 82% in BC and CRC respectively. Specificity rates for BC and CRC were 81% and 82%, and sensitivity was 75% and 82% respectively. Positive predictive value was 87% and 77%, and negative predictive value was 65% and 86% in BC and CRC respectively. The mean AUC for BC was 0.83 and 0.88 for CRC.
CONCLUSIONS
The EORTC-QLQ-C30 EF is useful for rapid screening. The systematic application of this scale would allow patients with cancer and emotional problems to be easily identified in clinical practice.
简介
目的是分析欧洲癌症研究与治疗组织生活质量问卷（EORTC-QLQ-C30）EF 子量表在检测乳腺癌（BC）和结直肠癌（CRC）患者情绪问题方面的有用性。
方法
进行了一项前瞻性、观察性、横断面研究。参与者完成了简明症状量表（BSI）和 EORTC-QLQ-C30。计算了以下心理测量特性：准确性、敏感性、阳性预测值、特异性和阴性预测值。
结果
分析的样本包括 445 名患者：202 名 BC 患者和 243 名 CRC 患者。共有 129 名 BC 患者（64%）和 104 名 CRC 患者（43%）根据 BSI 患有心理困扰。EORTC-QLQ-C30 EF 检测心理困扰的准确性分别为 BC 的 77%和 CRC 的 82%。BC 和 CRC 的特异性分别为 81%和 82%，敏感性分别为 75%和 82%。BC 的阳性预测值为 87%，CRC 的阳性预测值为 77%，BC 的阴性预测值为 65%，CRC 的阴性预测值为 86%。BC 的平均 AUC 为 0.83，CRC 的平均 AUC 为 0.88。
结论
EORTC-QLQ-C30 EF 可用于快速筛查。该量表的系统应用可以使临床实践中容易识别患有癌症和情绪问题的患者。
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