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急性精神科病房自杀预防治疗的可行性与可接受性:随机对照试验

Feasibility and acceptability of suicide prevention therapy on acute psychiatric wards: randomised controlled trial.

作者信息

Haddock Gillian, Pratt Daniel, Gooding Patricia A, Peters Sarah, Emsley Richard, Evans Emma, Kelly James, Huggett Charlotte, Munro Ailsa, Harris Kamelia, Davies Linda, Awenat Yvonne

机构信息

Professor of Clinical Psychology,Division of Psychology and Mental Health, School of Health Sciences,University of Manchester, Greater Manchester Mental Health NHS Foundation Trust (formerly Manchester Mental Health and Social Care Trust) and Manchester Academic Health Sciences Centre,UK.

Senior Lecturer in Clinical Psychology,Division of Psychology and Mental Health, School of Health Sciences,University of Manchester, Greater Manchester Mental Health NHS Foundation Trust (formerly Manchester Mental Health and Social Care Trust) and Manchester Academic Health Sciences Centre,UK.

出版信息

BJPsych Open. 2019 Jan;5(1):e14. doi: 10.1192/bjo.2018.85.

Abstract

BACKGROUND

Suicidal behaviour is common in acute psychiatric wards resulting in distress, and burden for patients, carers and society. Although psychological therapies for suicidal behaviour are effective in out-patient settings, there is little research on their effectiveness for in-patients who are suicidal.AimsOur primary objective was to determine whether cognitive-behavioural suicide prevention therapy (CBSP) was feasible and acceptable, compared with treatment as usual (TAU) for in-patients who are suicidal. Secondary aims were to assess the impact of CBSP on suicidal thinking, behaviours, functioning, quality of life, service use, cost-effectiveness and psychological factors associated with suicide.

METHOD

A single-blind pilot randomised controlled trial comparing TAU to TAU plus CBSP in in-patients in acute psychiatric wards who are suicidal (the Inpatient Suicide Intervention and Therapy Evaluation (INSITE) trial, trial registration: ISRCTN17890126). The intervention consisted of TAU plus up to 20 CBSP sessions, over 6 months continuing in the community following discharge. Participants were assessed at baseline and at 6 weeks and 6 months post-baseline.

RESULTS

A total of 51 individuals were randomised (27 to TAU, 24 to TAU plus CBSP) of whom 37 were followed up at 6 months (19 in TAU, 18 in TAU plus CBSP). Engagement, attendance, safety and user feedback indicated that the addition of CBSP to TAU for in-patients who are acutely suicidal was feasible and acceptable while on in-patient wards and following discharge. Economic analysis suggests the intervention could be cost-effective.DiscussionPsychological therapy can be delivered safely to patients who are suicidal although modifications are required for this setting. Findings indicate a larger, definitive trial should be conducted.Declaration of interestThe trial was hosted by Greater Manchester Mental health NHS Trust (formerly, Manchester Mental Health and Social Care NHS Trust). The authors are affiliated to the University of Manchester, Greater Manchester Mental Health Foundation Trust, Lancashire Care NHS Foundation trust and the Manchester Academic Health Sciences Centre. Y.A. is a trustee for a North-West England branch of the charity Mind.

摘要

背景

自杀行为在急性精神科病房很常见,会给患者、护理人员和社会带来痛苦和负担。虽然针对自杀行为的心理治疗在门诊环境中有效,但对于有自杀倾向的住院患者的有效性研究较少。

目的

我们的主要目标是确定与常规治疗(TAU)相比,认知行为自杀预防疗法(CBSP)对有自杀倾向的住院患者是否可行且可接受。次要目标是评估CBSP对自杀想法、行为、功能、生活质量、服务使用、成本效益以及与自杀相关的心理因素的影响。

方法

一项单盲试点随机对照试验,在急性精神科病房有自杀倾向的住院患者中比较TAU与TAU加CBSP(住院患者自杀干预和治疗评估(INSITE)试验,试验注册号:ISRCTN17890126)。干预措施包括TAU加上长达20次的CBSP治疗,为期6个月,并在出院后在社区继续进行。在基线、基线后6周和6个月对参与者进行评估。

结果

共有51人被随机分组(27人接受TAU,24人接受TAU加CBSP),其中37人在6个月时接受了随访(19人在TAU组,18人在TAU加CBSP组)。参与度、出勤率、安全性和用户反馈表明,在住院病房和出院后,对急性自杀倾向的住院患者在TAU基础上加用CBSP是可行且可接受的。经济分析表明该干预措施可能具有成本效益。

讨论

虽然在这种情况下需要进行调整,但心理治疗可以安全地提供给有自杀倾向的患者。研究结果表明应进行更大规模的确证性试验。

利益声明

该试验由大曼彻斯特精神健康国民保健服务信托基金(原曼彻斯特精神健康和社会护理国民保健服务信托基金)主办。作者隶属于曼彻斯特大学、大曼彻斯特精神健康基金会信托基金、兰开夏郡护理国民保健服务基金会信托基金和曼彻斯特学术健康科学中心。Y.A.是慈善机构“心智”在英格兰西北部一个分支机构的受托人。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aea7/6381415/0f715acd084a/S2056472418000856_fig1.jpg

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