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针灸治疗大便失禁:系统评价与数据挖掘方案

Acupuncture for fecal incontinence: Protocol for a systematic review and data mining.

作者信息

Lin Haixiong, Zhang Zhiqing, Hu Guijuan, Wang Xiaotong, Lin Chunni, Chen Yongjun

机构信息

The First School of Clinical Medicine.

South China Research Center for Acupuncture and Moxibustion.

出版信息

Medicine (Baltimore). 2019 Feb;98(7):e14482. doi: 10.1097/MD.0000000000014482.

DOI:10.1097/MD.0000000000014482
PMID:30762773
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6408071/
Abstract

BACKGROUND

Fecal incontinence is a socially and emotionally destructive condition that has a negative impact on personal image, self-confidence, and quality of life. Acupuncture is commonly used to treat chronic conditions, including fecal incontinence. However, no relevant systematic review or meta-analysis has been designed to evaluate the effects of acupuncture on fecal incontinence.

METHODS

We will identify relevant randomized controlled trials (RCTs) from the Cochrane Library, Medline, Embase, PubMed, Springer, Web of Science, China National Knowledge Infrastructure, VIP Chinese Science and Technology Journals Database, Wanfang database, and clinical trial registration center from their inception to February 28, 2019. The primary outcome measures will be clinical effective rate, functional outcomes, and quality of life. Data that meets the inclusion criteria will be extracted and analyzed using RevMan V.5.3 software. Two reviewers will evaluate the studies using the Cochrane Collaboration risk of bias tool. Publication bias will be assessed by funnel plots, Egger test, and Begg test using the Stata software. Acupoints characteristics will be analyzed by Traditional Chinese Medicine inheritance support system.

RESULTS

This study will analyze the clinical effective rate, functional outcomes, quality of life, daily average number of fecal incontinence, and effective prescriptions of acupuncture for patients with fecal incontinence.

CONCLUSION

Our findings will provide evidence for the effectiveness and potential treatment prescriptions of acupuncture for patients with fecal incontinence.

PROSPERO REGISTRATION NUMBER

PROSPERO CRD42019119680.

摘要

背景

大便失禁是一种对社交和情绪具有破坏性的病症,会对个人形象、自信心和生活质量产生负面影响。针灸常用于治疗包括大便失禁在内的慢性疾病。然而,尚未设计相关的系统评价或荟萃分析来评估针灸对大便失禁的疗效。

方法

我们将从Cochrane图书馆、Medline、Embase、PubMed、Springer、Web of Science、中国知网、维普中文科技期刊数据库、万方数据库以及临床试验注册中心检索从建库至2019年2月28日的相关随机对照试验(RCT)。主要结局指标将为临床有效率、功能结局和生活质量。符合纳入标准的数据将使用RevMan V.5.3软件进行提取和分析。两名评价者将使用Cochrane协作网偏倚风险工具对研究进行评估。将使用Stata软件通过漏斗图、Egger检验和Begg检验评估发表偏倚。将通过中医传承辅助系统分析穴位特征。

结果

本研究将分析针灸治疗大便失禁患者的临床有效率、功能结局、生活质量、每日大便失禁平均次数以及有效方剂。

结论

我们的研究结果将为针灸治疗大便失禁患者的有效性和潜在治疗方剂提供证据。

国际前瞻性注册系统登记号

PROSPERO CRD42019119680。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a424/6408071/6f66efb6502b/medi-98-e14482-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a424/6408071/6f66efb6502b/medi-98-e14482-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a424/6408071/6f66efb6502b/medi-98-e14482-g003.jpg

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