Institute of General Practice, Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany. Email:
Am J Manag Care. 2019 Feb 1;25(2):e45-e49.
To assess the performance of the adapted Diabetes Complications Severity Index (aDCSI) translated to International Classification of Diseases, Tenth Revision (ICD-10) in predicting hospitalizations, mortality, and healthcare-associated costs.
Retrospective closed cohort study based on secondary data analysis.
We translated the aDCSI to ICD-10 and calculated aDCSI scores based on health insurance claims data. To assess predictive performance, we used multivariate regression models to calculate risk ratios (RRs) of hospitalizations and mortality and linear predictors of cost.
We analyzed a sample of 157,115 patients with diabetes mellitus. RRs of hospitalizations (total and cause specific) rose with increasing aDCSI scores. Predicting total hospitalizations over a 4-year period, unadjusted RRs were 1.22 for an aDCSI score of 1 (compared with a score of 0), 1.55 for a score of 2, 1.77 for a score of 3, 2.11 for a score of 4, and 2.72 for scores of 5 and higher. Cause-specific hospitalizations and mortality showed similar results. Costs clearly increased in each successive score category.
Our study supports the validity of the aDCSI as a severity measure for complications of diabetes, as it correlates to and predicts total and cause-specific hospitalizations, mortality, and costs. The aDCSI's performance in ICD-10-coded data is comparable with that in International Classification of Diseases, Ninth Revision-coded data.
评估改编后的糖尿病并发症严重程度指数(aDCSI)在预测住院、死亡和医疗保健相关成本方面的表现,该指数已被译为国际疾病分类第 10 版(ICD-10)。
基于二次数据分析的回顾性封闭队列研究。
我们将 aDCSI 译为 ICD-10,并根据医疗保险索赔数据计算 aDCSI 评分。为了评估预测性能,我们使用多元回归模型计算住院和死亡率的风险比(RR)和成本的线性预测值。
我们分析了 157115 名糖尿病患者的样本。随着 aDCSI 评分的增加,住院(总住院和特定病因住院)的 RR 上升。在预测 4 年内的总住院情况时,未经调整的 RR 为 aDCSI 评分为 1(与评分为 0 相比)时为 1.22,评分为 2 时为 1.55,评分为 3 时为 1.77,评分为 4 时为 2.11,评分为 5 及以上时为 2.72。特定病因的住院和死亡率也呈现出类似的结果。每个连续的评分类别中,成本都明显增加。
我们的研究支持 aDCSI 作为糖尿病并发症严重程度的衡量标准的有效性,因为它与总住院和特定病因住院、死亡率和成本相关,并能预测这些指标。在 ICD-10 编码数据中,aDCSI 的性能与在国际疾病分类第 9 版编码数据中的性能相当。