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胎儿腹部囊肿:产前病程和产后结局。

Fetal abdominal cysts: antenatal course and postnatal outcomes.

机构信息

Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital, Imperial College Healthcare NHS Trust, London, UK.

Gynecologic and Obstetric Clinic, Department of Surgical, Microsurgical and Medical Sciences, University of Sassari, Sassari, Italy.

出版信息

J Perinat Med. 2019 May 27;47(4):418-421. doi: 10.1515/jpm-2018-0311.

Abstract

Background There is little information on which to base the prognostic counselling as to whether an antenatally diagnosed fetal abdominal cyst will grow or shrink, or need surgery. This study aims to provide contemporary data on prenatally diagnosed fetal abdominal cysts in relation to their course and postnatal outcomes. Methods Fetal abdominal cysts diagnosed over 11 years in a single centre were identified. The gestational age at diagnosis and cyst characteristics at each examination were recorded (size, location, echogenity, septation and vascularity) and follow-up data from postnatal visits were collected. Results Eighty abdominal cysts were identified antenatally at 28+4 weeks (range 11+0-38+3). Most (87%) were isolated and the majority were pelvic (52%), simple (87.5%) and avascular (100%). Antenatally, 29% resolved spontaneously; 29% reduced in size; 9% were stable and 33% increased in size. Forty-one percent of cysts under 20 mm diameter increased in size, while only 20% of cysts with a diameter of over 40 mm increased in size. The majority of cysts were ovarian in origin (n=45, 56%), followed by intestinal (n=15, 18%), choledochal (n=3, 4%), liver (n=2, 3%) and renal/adrenal origins (n=2, 3%), respectively. In 16% (n=13), the antenatal diagnosis was not obvious. Seventy-five percent of the cysts that persisted postnatally required surgical intervention. Conclusion Most antenatally diagnosed fetal abdominal cysts were ovarian in origin. Though most disappeared antenatally, nearly three quarters required surgical intervention when present after birth. Cysts of intestinal origin are more difficult to diagnose antenatally and often require surgery.

摘要

背景

对于产前诊断出的胎儿腹部囊肿是否会生长、缩小或需要手术,目前几乎没有信息可以作为预后咨询的依据。本研究旨在提供有关产前诊断出的胎儿腹部囊肿的最新数据,包括其病程和产后结局。

方法

在一家单中心回顾性分析了 11 年来产前诊断出的胎儿腹部囊肿。记录了每个检查时的胎龄和囊肿特征(大小、位置、回声、分隔和血管分布),并收集了产后就诊的随访数据。

结果

在 28+4 周(范围 11+0-38+3)时,产前共发现 80 个腹部囊肿。大多数(87%)为孤立性囊肿,大多数位于骨盆(52%),大多数为单纯性(87.5%)和无血管性(100%)。产前囊肿有 29%自发消退,29%缩小,9%稳定,33%增大。20mm 以下直径的囊肿中 41%增大,而 40mm 以上直径的囊肿中仅 20%增大。大多数囊肿来源于卵巢(n=45,56%),其次是肠源性(n=15,18%)、胆总管(n=3,4%)、肝源性(n=2,3%)和肾/肾上腺源性(n=2,3%)。16%(n=13)的囊肿产前诊断不明确。75%的囊肿持续存在于产后,需要手术干预。

结论

大多数产前诊断出的胎儿腹部囊肿来源于卵巢。尽管大多数囊肿在产前消失,但近四分之三的囊肿在出生后存在时需要手术干预。肠源性囊肿在产前更难诊断,通常需要手术。

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