Department of Internal Medicine, Okmeydanı Education and Research Hospital, Istanbul, Turkey,
Department of Pathology, Okmeydanı Education and Research Hospital, Istanbul, Turkey.
Med Princ Pract. 2020;29(1):90-93. doi: 10.1159/000498909. Epub 2019 Feb 14.
Whipple's disease is a very rare systemic infectious disease with an annual incidence of 3 in one million, which may be fatal if not diagnosed and treated appropriately.
Herein we describe a 49-year-old patient admitted to the hospital with symptoms of severe malabsorption and diagnosed with Whipple's disease. The diagnosis was based on the histopathological findings of small intestine biopsies and PCR analysis.
Whipple's disease should be kept in mind while dealing with patients with severe malabsorption, even in the absence of accompanying features of the disease.
Whipple 病是一种非常罕见的全身性感染性疾病,年发病率为每百万人中有 3 例,如果诊断和治疗不当,可能致命。
本文描述了一位 49 岁的患者,因严重吸收不良症状入院,被诊断为 Whipple 病。诊断依据为小肠活检的组织病理学发现和 PCR 分析。
在处理严重吸收不良的患者时,即使没有伴随该病的特征,也应考虑 Whipple 病。