Instituto de Tecnologías de la Información y Comunicaciones (ITACA), Universitat Politècnica de València, Camino de Vera s/n, 46022 Valencia, Spain.
Instituto Universitario de Matemática Pura y Aplicada, Universitat Politècnica de València, Camino de Vera s/n, 46022 Valencia, Spain.
Int J Environ Res Public Health. 2019 Feb 5;16(3):461. doi: 10.3390/ijerph16030461.
Quality of life (QoL) indicators are now being adopted as clinical outcomes in clinical trials on cancer treatments. Technology-free daily monitoring of patients is complicated, time-consuming and expensive due to the need for vast amounts of resources and personnel. The alternative method of using the patients' own phones could reduce the burden of continuous monitoring of cancer patients in clinical trials. This paper proposes monitoring the patients' QoL by gathering data from their own phones. We considered that the continuous multiparametric acquisition of movement, location, phone calls, conversations and data use could be employed to simultaneously monitor their physical, psychological, social and environmental aspects. An open access phone app was developed (Human Dynamics Reporting Service (HDRS)) to implement this approach. We here propose a novel mapping between the standardized QoL items for these patients, the European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) and define HDRS monitoring indicators. A pilot study with university volunteers verified the plausibility of detecting human activity indicators directly related to QoL.
生活质量（QoL）指标现在被用作癌症治疗临床试验的临床结果。由于需要大量的资源和人员，因此，对患者进行无技术日常监测既复杂又耗时且昂贵。使用患者自己的手机的替代方法可以减轻临床试验中对癌症患者持续监测的负担。本文提出通过从患者自己的手机中收集数据来监测患者的 QoL。我们认为，可以连续多参数采集运动、位置、电话、对话和数据使用情况，以同时监测他们的身体、心理、社会和环境方面。开发了一个开放访问的电话应用程序（Human Dynamics Reporting Service (HDRS））来实现这种方法。我们在这里提出了一种新的映射，将这些患者的标准化 QoL 项目与欧洲癌症研究与治疗组织生活质量问卷（EORTC QLQ-C30）联系起来，并定义了 HDRS 监测指标。一项针对大学志愿者的试点研究验证了直接检测与 QoL 直接相关的人类活动指标的合理性。
