Health Research Center of Angola (CISA), Caxito, Estação Central de Luanda, Apartado IV n°5547, Luanda, Angola.
Institute of Public Health, University of Porto, 4050-091 Porto, Portugal.
Int J Environ Res Public Health. 2019 Feb 5;16(3):466. doi: 10.3390/ijerph16030466.
Angola reports one of the highest infant mortality rates in the world, and anemia represents one of its important causes. Recent studies, in under-five children from the Bengo province of Angola, described high prevalence's, suggesting malaria, undernutrition and urogenital schistosomiasis as important contributors for the occurrence and spatial variations of anemia. Educational community-based interventions, either in Nutrition and Water, Sanitation, Hygiene and Malaria are recommended to correct anemia. Herein, we designed a cluster-randomized controlled trial to study the efficacy of two educational-plus-therapeutic interventions in the reduction of anemia: one in nutrition and the other in WASH/Malaria. Socioeconomic, nutritional, anthropometric, parasitological and biochemical data will be collected from all willing-to-participate children, aging under four and resident in the Health Research Center of Angola study area. Considering the multifactorial causes of this condition, determining the efficacy of both interventions might help documenting weaknesses and opportunities for planning integrated strategies to reduce anemia.
安哥拉报告称其拥有世界上最高的婴儿死亡率之一，而贫血症是其重要原因之一。最近的研究表明，安哥拉本戈省五岁以下儿童贫血症的发病率较高，提示疟疾、营养不良和尿路血吸虫病是导致贫血症发生和空间变异的重要因素。建议开展以社区为基础的教育干预，包括营养、水、环境卫生和疟疾等方面的干预，以纠正贫血症。在此，我们设计了一项整群随机对照试验，以研究两种教育加治疗干预措施在降低贫血症方面的疗效：一种是营养干预，另一种是水、环境卫生和疟疾干预。我们将从所有愿意参与的年龄在四岁以下、居住在安哥拉卫生研究中心研究区域的儿童中收集社会经济、营养、人体测量学、寄生虫学和生物化学数据。考虑到这种情况的多种因素，确定这两种干预措施的疗效可能有助于记录薄弱环节和规划综合战略的机会，以降低贫血症的发病率。
