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营养和 WASH/疟疾教育社区干预措施在减少安哥拉儿童贫血方面的效果。

Effectiveness of Nutrition and WASH/malaria educational community-based interventions in reducing anemia in children from Angola.

机构信息

Health Research Center of Angola (CISA, Translated), Caxito, Angola.

Instituto de Saúde Pública da Universidade Do Porto, Porto, Portugal.

出版信息

Sci Rep. 2021 Mar 10;11(1):5603. doi: 10.1038/s41598-021-85006-x.

Abstract

We found no published data in Angola regarding the effect of combining nutrition-specific and nutrition-sensitive approaches in the reduction of anemia in preschool children. Thus, we implemented a cluster-randomized controlled trial to determine the effectiveness of two educational-plus-therapeutic interventions, in Nutrition and WASH/Malaria, in reducing anemia. We compared them to (1) a test-and-treat intervention and (2) with each other. A block randomization was performed to allocate 6 isolated hamlets to 3 study arms. A difference-in-difference technique, using Fit Generalized estimating models, was used to determine differences between the children successfully followed in all groups, between 2015 and 2016. We found no significant differences in anemia´s and hemoglobin variability between educational and the control group. However, the WASH/Malaria group had 22.8% higher prevalence of anemia when compared with the Nutrition group, having also higher prevalence of P. falciparum. Thus, our results suggest that adding a 12-month educational Nutrition or a WASH/Malaria component to a test-and-treat approach may have a limited effect in controlling anemia. Possibly, the intensity and duration of the educational interventions were not sufficient to observe the amount of behavior change needed to stop transmission and improve the general child feeding practices.

摘要

我们在安哥拉没有发现任何关于结合营养特定和营养敏感方法来减少学龄前儿童贫血的影响的已发表数据。因此,我们实施了一项集群随机对照试验,以确定营养和 WASH/疟疾中的两种教育加治疗干预措施在减少贫血方面的有效性。我们将它们与(1)检测和治疗干预措施进行了比较,并相互进行了比较。采用块随机化方法将 6 个孤立的小村庄分配到 3 个研究组中。采用差异-差异技术,使用 Fit 广义估计模型,确定了所有组中成功随访的儿童在 2015 年至 2016 年期间的差异。我们没有发现教育组和对照组之间的贫血和血红蛋白变异性存在显著差异。然而,与营养组相比,WASH/疟疾组的贫血患病率高 22.8%,并且疟原虫感染的患病率也更高。因此,我们的结果表明,在检测和治疗方法中添加为期 12 个月的营养或 WASH/疟疾教育内容可能对控制贫血的效果有限。可能是教育干预的强度和持续时间不足以观察到需要改变行为以停止传播并改善儿童一般喂养习惯的程度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3ee/7946872/e9724e8d5180/41598_2021_85006_Fig1_HTML.jpg

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