Insititut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Barcelona, Spain.
Diabetes Care. 2019 Apr;42(4):514-519. doi: 10.2337/dc18-1471. Epub 2019 Feb 14.
An association between variability in clinical parameters (HbA, blood pressure, cholesterol, and uric acid) and risk of complications in type 2 diabetes has been reported. In this analysis, we investigated to what extent such variability is associated with overall quality of care.
The quality of care summary score (Q-score) represents a validated, overall quality of care indicator ranging between 0 and 40; the higher the score, the better the quality of care provided by the diabetes center. We identified patients with five or more measurements of clinical parameters after the assessment of the Q-score. Multiple linear regression analyses assessed the role of the Q-score in predicting the variability of the different parameters.
Overall, 273,888 patients were analyzed. The variability of all the parameters systematically increased with decreasing Q-score values. At multivariate linear regression analysis, compared with a Q-score >25, a score <15 was associated with a significantly larger variation in HbA, blood pressure, uric acid, total cholesterol, and LDL cholesterol and a lower variation in HDL cholesterol. The analysis of standardized β coefficients show that the Q-score has a larger impact on the variability of HbA (0.34; < 0.0001), systolic blood pressure (0.21; < 0.0001), total cholesterol (0.21; < 0.0001), and LDL cholesterol (0.20; < 0.0001).
The variability of risk factors for diabetic complications is associated with quality of care. Quality of care improvement initiatives should be targeted to increase the achievement of the recommended target while reducing such variability.
已有研究报道,2 型糖尿病患者的临床参数(HbA、血压、胆固醇和尿酸)变化与并发症风险之间存在关联。在本分析中,我们研究了这种变化在多大程度上与整体护理质量相关。
护理质量综合评分(Q 评分)代表一种经过验证的整体护理质量指标,范围在 0 到 40 之间;评分越高,糖尿病中心提供的护理质量越好。我们确定了在评估 Q 评分后有 5 次或以上临床参数测量值的患者。采用多元线性回归分析评估 Q 评分在预测不同参数变化中的作用。
共分析了 273888 例患者。所有参数的变化均随 Q 评分值的降低而系统性增加。在多元线性回归分析中,与 Q 评分>25 相比,Q 评分<15 与 HbA、血压、尿酸、总胆固醇和 LDL 胆固醇的变化显著增大以及 HDL 胆固醇的变化显著减小相关。标准化β系数分析表明,Q 评分对 HbA(0.34;<0.0001)、收缩压(0.21;<0.0001)、总胆固醇(0.21;<0.0001)和 LDL 胆固醇(0.20;<0.0001)的变化影响更大。
糖尿病并发症风险因素的变化与护理质量相关。应针对护理质量改进措施,在提高达标率的同时,减少这种变化。