Alhossan Abdulaziz, Alrabiah Ziyad, Alghadeer Sultan, Bablghaith Salmeen, Wajid Syed, Al-Arifi Mohammed
Department of Clinical Pharmacy, King Saud University, Saudi Arabia.
Department of Basic Sciences, Prince Sultan Bin Abdulaziz College for Emergency Medical Services, King Saud University, Saudi Arabia.
Saudi Pharm J. 2019 Feb;27(2):225-228. doi: 10.1016/j.jsps.2018.11.002. Epub 2018 Nov 7.
Proton pump inhibitors (PPIs) effectively suppress acid secretion and play an important role in peptic ulcer disease and gastroesophageal reflux disease There is a real concern about the overutilization of PPIs, which will lead to significant high cost and undesirable outcomes Despite that most of PPIs are classified as prescribed medications, yet most of their users take them without prescription in Saudi Arabia. Therefore, it was important to understand community pharmacists practice in dealing with PPIs and to evaluate their despising pattern of these medications.
A cross-sectional survey-based study that was carried out between September and December 2017. The survey intended to evaluate the knowledge and attitude of CPs towards use of proton pump inhibitors and was built as an online survey.
The results of this study showed that almost all CPs prescribe anti-ulcer drugs for their patients Most of the participants (68.4%) have prescribed PPI for acute gastritis (68.4%), prophylaxis for stress ulcers (17.7%) and stress ulcer (11.1%). 54.9 percent of the participants recommend using acid suppression drugs for 1 to 2 weeks when they prescribe them to their patients Thirty-two percent of the respondents had reported adverse events with PPIs. The study showed a significant association between length of work experience in community pharmacy and reporting adverse events.
Community pharmacists in Saudi Arabia usually recommend and prescribe PPIs to their patients. Most of them have some knowledge on PPIs indications and side effects. Managing OTC PPI use in the community pharmacy setting is necessary to promote both patient and medication safety.
质子泵抑制剂(PPIs)能有效抑制胃酸分泌,在消化性溃疡疾病和胃食管反流病中发挥重要作用。人们对PPIs的过度使用深感担忧,因为这会导致高昂的成本和不良后果。尽管大多数PPIs被归类为处方药,但在沙特阿拉伯,大多数使用者在没有处方的情况下服用这些药物。因此,了解社区药剂师在处理PPIs方面的做法并评估他们对这些药物的轻视模式很重要。
2017年9月至12月进行了一项基于横断面调查的研究。该调查旨在评估社区药剂师对使用质子泵抑制剂的知识和态度,并构建为在线调查。
本研究结果表明,几乎所有社区药剂师都为患者开具抗溃疡药物。大多数参与者(68.4%)为急性胃炎(68.4%)、应激性溃疡预防(17.7%)和应激性溃疡(11.1%)开具了PPI。54.9%的参与者在给患者开这些药时建议使用抑酸药物1至2周。32%的受访者报告了PPIs的不良事件。该研究表明,社区药房工作经验的长短与报告不良事件之间存在显著关联。
沙特阿拉伯的社区药剂师通常会向患者推荐并开具PPIs。他们中的大多数人对PPIs的适应症和副作用有一定了解。在社区药房环境中管理非处方PPI的使用对于促进患者和用药安全是必要的。