Rubin E H
Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110.
Psychiatr Dev. 1988 Winter;6(4):329-37.
Geriatric psychiatry involves the study of the interaction of age, medical illnesses, psychopathology, and treatment responsivity. Many of these interactions are demonstrated by reviewing mania in the elderly. Studying geriatric aspects of psychiatric disorders may give clues to understanding the pathophysiology of the same disorder in younger patients. For instance, localization of lesions associated with late onset mania suggests brain areas which may be involved in the early onset form of bipolar affective disorder. Reviewing the use of lithium in the elderly patient with mania provides the opportunity to review general geriatric psychopharmacologic principles.
老年精神病学涉及对年龄、躯体疾病、精神病理学和治疗反应性之间相互作用的研究。通过回顾老年人的躁狂症可以展现其中许多相互作用。研究精神障碍的老年方面可能为理解年轻患者相同障碍的病理生理学提供线索。例如,与晚发性躁狂症相关的病变定位提示了可能参与双相情感障碍早发性形式的脑区。回顾锂盐在老年躁狂症患者中的应用为复习一般老年精神药理学原则提供了机会。