Masresha Balcha, Luce Richard, Shibeshi Messeret, Katsande Reggis, Fall Amadou, Okeibunor Joseph, Weldegebriel Goitom, Mihigo Richard
WHO Regional Office for Africa, Brazzaville, Congo.
WHO Inter-country Support Team for Central Africa, Libreville, Gabon.
J Immunol Sci. 2018 Jul 28;Suppl:140-144.
Measles elimination is defined as the absence of endemic measles virus transmission in a defined geographic area for at least 12 months in the presence of a well-performing surveillance system. The WHO framework for verification of measles elimination indicates that the achievement of measles and/or rubella elimination should be verified for individual countries.
We identified 11 high performing countries based on their first dose measles vaccination coverage, and looked at their performance across the various programmatic parameters, to see if they are ready to undertake the verification of measles elimination.
We identified 11 countries with >90% measles first dose coverage for the most recent 5 years according to the WHO UNICEF estimates of national immunisation coverage. We analysed vaccination coverage and surveillance performance in these countries.
Algeria, Botswana, Gambia, Mauritius, Rwanda, Seychelles have maintained measles first dose (MCV1) coverage of 95% or more since 2011. In 2015, only Algeria, Cape Verde and Seychelles had coverage of 95% or more for the second dose of measles vaccine (MCV2). Of the 22 supplemental immunisation activities (SIAs) among the 11 countries, only 6 had administrative coverage of less than 95%. Only Rwanda and Lesotho attained the case-based surveillance performance targets in all the five years.
Despite their high routine first dose measles immunisation coverage, all of the 11 countries have some program gaps indicating that they do not meet all the criteria to undergo verification of elimination at this point. It is recommended for these countries to set up national verification committees as per the WHO framework for verification of measles elimination, in order to initiate the documentation and monitoring of progress, and to address programmatic gaps in the coming years.
消除麻疹的定义是在运转良好的监测系统存在的情况下,在特定地理区域内至少12个月没有地方性麻疹病毒传播。世卫组织麻疹消除验证框架表明,应针对各个国家对麻疹和/或风疹消除的实现情况进行验证。
我们根据11个国家的首剂麻疹疫苗接种覆盖率确定了这些表现出色的国家,并研究了它们在各项规划参数方面的表现,以确定它们是否准备好进行麻疹消除验证。
根据世卫组织/联合国儿童基金会对国家免疫覆盖率的估计,我们确定了11个在最近5年麻疹首剂覆盖率超过90%的国家。我们分析了这些国家的疫苗接种覆盖率和监测表现。
自2011年以来,阿尔及利亚、博茨瓦纳、冈比亚、毛里求斯、卢旺达、塞舌尔的麻疹首剂(MCV1)覆盖率保持在95%或更高。2015年,只有阿尔及利亚、佛得角和塞舌尔的麻疹疫苗第二剂(MCV2)覆盖率达到95%或更高。在这11个国家的22次补充免疫活动(SIAs)中,只有6次行政覆盖率低于95%。只有卢旺达和莱索托在所有五年中都达到了基于病例的监测表现目标。
尽管这11个国家的首剂麻疹常规免疫覆盖率很高,但所有国家都存在一些规划差距,这表明它们目前尚未满足进行消除验证的所有标准。建议这些国家按照世卫组织麻疹消除验证框架设立国家验证委员会,以便启动进展情况的记录和监测,并在未来几年解决规划差距问题。