Division of General Surgery, National University Health System, 1E, Kent Ridge Road, Singapore, 119228, Singapore.
Epidemiology and Public Health, Saw Swee Hock School of Public Health, National University of Singapore, 12 Science Drive 2, #10-01, Singapore, 117549, Singapore.
Obes Surg. 2019 Jun;29(6):1781-1788. doi: 10.1007/s11695-019-03716-8.
Prevalence of obesity in Asia has been on the increasing trend, with corresponding increase in utilisation of bariatric surgery. The objective of this study was to examine differences in weight loss outcomes following bariatric surgery between Asian ethnicities.
A retrospective database review was conducted of patients undergoing primary laparoscopic sleeve gastrectomy between 2009 and 2013 in 14 centres from Singapore, Malaysia, Taiwan, Hong Kong, Japan, Korea, India, Australia, Switzerland, and the USA. All patients with available follow-up data at 12 months and 36 months post-surgery were included in this study. Outcome measures used were percentage excess weight loss (%EWL) and percentage total weight loss (%TWL). Differences in outcomes between ethnicities were analysed after adjusting for age, gender, baseline body mass index (BMI), and presence of diabetes.
The study population (n = 2150) consisted of 1122 Chinese, 187 Malays, 309 Indians, 67 Japanese, 259 Koreans, and 206 Caucasians. 67.1% were female and 32.9% were male. Mean age was 37.1 ± 11.2 years. Mean pre-operative BMI was 40.7 ± 8.1 kg/m. With the Caucasian population as reference, Japanese had the best %TWL (3.90, 95% CI 1.16-6.63, p < 0.05) and %EWL (18.55, 95% CI 10.33-26.77, p < 0.05) while the Malays had the worst outcomes. Both Chinese and Koreans had better %EWL but worse %TWL as compared to Caucasians and there were no significant differences with the Indian study group.
There are differences in weight loss outcomes following bariatric surgery between Asian ethnicities.
亚洲地区的肥胖患病率呈上升趋势，相应地，减重手术的应用也有所增加。本研究旨在探讨亚洲不同种族人群行减重手术后体重减轻效果的差异。
对 2009 年至 2013 年期间，来自新加坡、马来西亚、中国台湾、中国香港、日本、韩国、印度、澳大利亚、瑞士和美国的 14 个中心的 2150 例行腹腔镜袖状胃切除术患者进行了回顾性数据库研究。本研究纳入了所有在术后 12 个月和 36 个月时具有随访数据的患者。采用体重减轻百分比（%EWL）和总体重减轻百分比（%TWL）作为评估指标。对不同种族人群之间的结果差异，在调整了年龄、性别、基线体重指数（BMI）和糖尿病的存在后进行了分析。
研究人群（n=2150）包括 1122 名中国人、187 名马来人、309 名印度人、67 名日本人、259 名韩国人和 206 名高加索人。67.1%为女性，32.9%为男性。平均年龄为 37.1±11.2 岁。平均术前 BMI 为 40.7±8.1kg/m²。以高加索人群为参照，日本人的 %TWL（3.90，95%CI 1.16-6.63，p<0.05）和 %EWL（18.55，95%CI 10.33-26.77，p<0.05）最佳，而马来人的结果最差。中国人和韩国人的 %EWL 优于高加索人，但 %TWL 较其差，与印度研究组之间无显著差异。
亚洲不同种族人群行减重手术后体重减轻效果存在差异。
