1 型糖尿病运动的碳水化合物需求：胰岛素浓度的影响。
Carbohydrate Requirement for Exercise in Type 1 Diabetes: Effects of Insulin Concentration.
机构信息
Department of Medicine, University of Udine, Udine, Italy.
Department of Engineering and Architecture, University of Trieste, Trieste, Italy.
出版信息
J Diabetes Sci Technol. 2020 Nov;14(6):1116-1121. doi: 10.1177/1932296819826962. Epub 2019 Feb 15.
Abstract
Physical activity is a keystone of a healthy lifestyle as well as of management of patients with type 1 diabetes. The risk of exercise-induced hypoglycemia, however, is a great challenge for these patients. The glycemic response to exercise depends upon several factors concerning the patient him/herself (eg, therapy, glycemic control, training level) and the characteristics of the exercise performed. Only in-depth knowledge of these factors will allow to develop individualized strategies minimizing the risk of hypoglycemia. The main factors affecting the exercise-induced hypoglycemia in patients with T1D have been analyzed, including the effects of insulin concentration. A model is discussed, which has the potential to become the basis for providing patients with individualized suggestions to keep constant glucose levels on each exercise occasion.
摘要
体育活动是健康生活方式的基石，也是 1 型糖尿病患者管理的重要组成部分。然而，运动引起的低血糖风险对这些患者来说是一个巨大的挑战。运动引起的血糖反应取决于与患者自身相关的多个因素（例如，治疗、血糖控制、训练水平）和运动的特点。只有深入了解这些因素，才能制定出将低血糖风险降到最低的个体化策略。本文分析了影响 1 型糖尿病患者运动性低血糖的主要因素，包括胰岛素浓度的影响。还讨论了一个模型，该模型有可能成为为患者提供个性化建议的基础，以保持每次运动时血糖水平的稳定。
相似文献
1
Carbohydrate Requirement for Exercise in Type 1 Diabetes: Effects of Insulin Concentration.1 型糖尿病运动的碳水化合物需求：胰岛素浓度的影响。
J Diabetes Sci Technol. 2020 Nov;14(6):1116-1121. doi: 10.1177/1932296819826962. Epub 2019 Feb 15.
2
Effect of insulin therapy and dietary adjustments on safety and performance during simulated soccer tests in people with type 1 diabetes: study protocol for a randomized controlled trial.胰岛素治疗和饮食调整对1型糖尿病患者模拟足球测试期间安全性及运动表现的影响：一项随机对照试验的研究方案
Trials. 2017 Jul 20;18(1):338. doi: 10.1186/s13063-017-2078-1.
3
Simulation-Based Evaluation of Treatment Adjustment to Exercise in Type 1 Diabetes.基于模拟的 1 型糖尿病运动治疗调整评估。
Front Endocrinol (Lausanne). 2021 Aug 19;12:723812. doi: 10.3389/fendo.2021.723812. eCollection 2021.
4
Extent and prevalence of post-exercise and nocturnal hypoglycemia following peri-exercise bolus insulin adjustments in individuals with type 1 diabetes.1 型糖尿病患者运动前后调整胰岛素冲击量后运动后和夜间低血糖的程度和发生率。
Nutr Metab Cardiovasc Dis. 2021 Jan 4;31(1):227-236. doi: 10.1016/j.numecd.2020.07.043. Epub 2020 Aug 6.
5
Factors Associated With Glycemic Control During Free-Living Overnight Closed-Loop Insulin Delivery in Children and Adults With Type 1 Diabetes.1型糖尿病儿童和成人在自由生活的夜间闭环胰岛素给药期间与血糖控制相关的因素。
J Diabetes Sci Technol. 2015 Oct 7;9(6):1346-7. doi: 10.1177/1932296815604439.
6
Automatic data processing to achieve a safe telemedical artificial pancreas.通过自动数据处理实现安全的远程医疗人工胰腺。
J Diabetes Sci Technol. 2009 Sep 1;3(5):1039-46. doi: 10.1177/193229680900300507.
7
Comprehensive Analysis of the Real Lifestyles of T1D Patients for the Purpose of Designing a Personalized Counselor for Prandial Insulin Dosing.全面分析 T1D 患者的真实生活方式，旨在为餐前胰岛素剂量设计个性化咨询师。
Nutrients. 2019 May 23;11(5):1148. doi: 10.3390/nu11051148.
8
The bionic pancreas: novel perspectives on insulin replacement therapies.仿生胰腺：胰岛素替代疗法的新视角。
Transplantation. 2015 Feb;99(2):268-9. doi: 10.1097/TP.0000000000000544.
9
Efficacy of Carbohydrate Supplementation Compared With Bolus Insulin Dose Reduction Around Exercise in Adults With Type 1 Diabetes: A Retrospective, Controlled Analysis.碳水化合物补充对 1 型糖尿病成人运动时减少胰岛素剂量的效果：回顾性对照分析。
Can J Diabetes. 2020 Dec;44(8):697-700. doi: 10.1016/j.jcjd.2020.03.003. Epub 2020 Mar 22.
10
The Need to Change Regulatory Evaluation of Hypoglycemia in Trials of Diabetes Treatments.糖尿病治疗试验中改变低血糖监管评估的必要性。
J Diabetes Sci Technol. 2020 Nov;14(6):987-989. doi: 10.1177/1932296819891036. Epub 2019 Nov 19.
引用本文的文献
1
Effects of postprandial exercise on blood glucose levels in adults with type 1 diabetes: a review.餐后运动对 1 型糖尿病成人血糖水平的影响：综述。
Diabetologia. 2023 Jul;66(7):1179-1191. doi: 10.1007/s00125-023-05910-x. Epub 2023 Apr 4.
2
Protective effects of physical activity against health risks associated with type 1 diabetes: "Health benefits outweigh the risks".体育活动对1型糖尿病相关健康风险的保护作用：“健康益处大于风险”
World J Diabetes. 2022 Mar 15;13(3):161-184. doi: 10.4239/wjd.v13.i3.161.
3
Personalized Approach for the Management of Exercise-Related Glycemic Imbalances in Type 1 Diabetes: Comparison with Reference Method.1 型糖尿病运动相关血糖失衡管理的个体化方法：与参考方法的比较。
J Diabetes Sci Technol. 2021 Sep;15(5):1153-1160. doi: 10.1177/1932296820945372. Epub 2020 Aug 1.
4
Exercise Management for Young People With Type 1 Diabetes: A Structured Approach to the Exercise Consultation.1型糖尿病青少年的运动管理：运动咨询的结构化方法
Front Endocrinol (Lausanne). 2019 Jun 14;10:326. doi: 10.3389/fendo.2019.00326. eCollection 2019.
本文引用的文献
1
Could Age, Sex and Physical Fitness Affect Blood Glucose Responses to Exercise in Type 1 Diabetes?年龄、性别和身体素质会影响1型糖尿病患者运动后的血糖反应吗？
Front Endocrinol (Lausanne). 2018 Nov 15;9:674. doi: 10.3389/fendo.2018.00674. eCollection 2018.
2
Exercise modes and their association with hypoglycemia episodes in adults with type 1 diabetes mellitus: a systematic review.1型糖尿病成年患者的运动模式及其与低血糖发作的关联：一项系统评价
BMJ Open Diabetes Res Care. 2018 Oct 8;6(1):e000578. doi: 10.1136/bmjdrc-2018-000578. eCollection 2018.
3
Efficacy and safety of the artificial pancreas in the paediatric population with type 1 diabetes.人工胰腺在 1 型糖尿病儿童中的疗效和安全性。
J Transl Med. 2018 Jun 28;16(1):176. doi: 10.1186/s12967-018-1558-8.
4
Sex-related differences in fuel utilization and hormonal response to exercise: implications for individuals with type 1 diabetes.性别相关的燃料利用和激素对运动的反应差异：对 1 型糖尿病个体的影响。
Appl Physiol Nutr Metab. 2018 Jun;43(6):541-552. doi: 10.1139/apnm-2017-0559. Epub 2018 Feb 8.
5
Attitudes and barriers to exercise in adults with a recent diagnosis of type 1 diabetes: a qualitative study of participants in the Exercise for Type 1 Diabetes (EXTOD) study.近期诊断为1型糖尿病的成年人对运动的态度和障碍：1型糖尿病运动研究（EXTOD）参与者的定性研究
BMJ Open. 2018 Jan 24;8(1):e017813. doi: 10.1136/bmjopen-2017-017813.
6
Insulin Sensitivity Index-Based Optimization of Insulin to Carbohydrate Ratio: In Silico Study Shows Efficacious Protection Against Hypoglycemic Events Caused by Suboptimal Therapy.基于胰岛素敏感性指数的胰岛素与碳水化合物比值优化：模拟研究表明，针对治疗不足引起的低血糖事件具有有效的保护作用。
Diabetes Technol Ther. 2018 Feb;20(2):98-105. doi: 10.1089/dia.2017.0248.
7
Physical Activity Reduces Risk of Premature Mortality in Patients With Type 1 Diabetes With and Without Kidney Disease.体力活动可降低有和无肾病的 1 型糖尿病患者的过早死亡率。
Diabetes Care. 2017 Dec;40(12):1727-1732. doi: 10.2337/dc17-0615. Epub 2017 Oct 16.
8
Unhealthy lifestyle habits and diabetes-specific health-related quality of life in youths with type 1 diabetes.1型糖尿病青少年的不健康生活方式习惯与糖尿病特异性健康相关生活质量
Acta Diabetol. 2017 Dec;54(12):1073-1080. doi: 10.1007/s00592-017-1051-5. Epub 2017 Sep 15.
9
Closed-Loop Control During Intense Prolonged Outdoor Exercise in Adolescents With Type 1 Diabetes: The Artificial Pancreas Ski Study.1型糖尿病青少年高强度长时间户外运动期间的闭环控制：人工胰腺滑雪研究
Diabetes Care. 2017 Dec;40(12):1644-1650. doi: 10.2337/dc17-0883. Epub 2017 Aug 30.
10
Boiling factors in the pot of type 1 diabetes mellitus management: the role of exercise.1型糖尿病管理之锅的关键因素：运动的作用
Med Hypotheses. 2017 Aug;105:48. doi: 10.1016/j.mehy.2017.06.026. Epub 2017 Jun 28.
Zotero 插件