Department of Medicine, University of Udine, Udine, Italy.
Department of Engineering and Architecture, University of Trieste, Trieste, Italy.
J Diabetes Sci Technol. 2020 Nov;14(6):1116-1121. doi: 10.1177/1932296819826962. Epub 2019 Feb 15.
Physical activity is a keystone of a healthy lifestyle as well as of management of patients with type 1 diabetes. The risk of exercise-induced hypoglycemia, however, is a great challenge for these patients. The glycemic response to exercise depends upon several factors concerning the patient him/herself (eg, therapy, glycemic control, training level) and the characteristics of the exercise performed. Only in-depth knowledge of these factors will allow to develop individualized strategies minimizing the risk of hypoglycemia. The main factors affecting the exercise-induced hypoglycemia in patients with T1D have been analyzed, including the effects of insulin concentration. A model is discussed, which has the potential to become the basis for providing patients with individualized suggestions to keep constant glucose levels on each exercise occasion.
体育活动是健康生活方式的基石，也是 1 型糖尿病患者管理的重要组成部分。然而，运动引起的低血糖风险对这些患者来说是一个巨大的挑战。运动引起的血糖反应取决于与患者自身相关的多个因素（例如，治疗、血糖控制、训练水平）和运动的特点。只有深入了解这些因素，才能制定出将低血糖风险降到最低的个体化策略。本文分析了影响 1 型糖尿病患者运动性低血糖的主要因素，包括胰岛素浓度的影响。还讨论了一个模型，该模型有可能成为为患者提供个性化建议的基础，以保持每次运动时血糖水平的稳定。
