色素失禁症（布洛赫-苏尔茨贝格综合征）双侧视网膜血管阻塞行玻璃体腔注射贝伐单抗及激光治疗后的血管再通
Revascularization After Intravitreal Bevacizumab and Laser Therapy of Bilateral Retinal Vascular Occlusions in Incontinentia Pigmenti (Bloch-Sulzberger Syndrome).
作者信息
Cernichiaro-Espinosa Linda A, Patel Nimesh A, Bauer Mislen S, Negron Catherin I, Fallas Brenda, Pogrebniak Alexander, Berrocal Audina M
出版信息
Ophthalmic Surg Lasers Imaging Retina. 2019 Feb 1;50(2):e33-e37. doi: 10.3928/23258160-20190129-16.
No consensus exists for the treatment of retinopathy in incontinentia pigmenti (IP). Vascular ischemia leads to tractional retinal detachments if untreated. Ultra-widefield fluorescein angiography (FA) is used to follow the vascular status of the retina. A 13-week-old female with IP presented with bilateral retinal vascular occlusions in both eyes. Ultra-widefield FA showed reperfusion after treatment with intravitreal bevacizumab (IVB) and angiography-guided laser to the avascular retina. Anti-vascular endothelial growth factor treatment reduces neovascularization and allows for growth of retinal vessels. IVB and FA-guided laser to the avascular retina is an option in IP. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:e33-e37.].
对于色素失禁症（IP）视网膜病变的治疗尚无共识。若不治疗，血管缺血会导致牵引性视网膜脱离。超广角荧光素血管造影（FA）用于监测视网膜的血管状态。一名13周大的患有IP的女性双眼出现双侧视网膜血管阻塞。超广角FA显示，玻璃体内注射贝伐单抗（IVB）并对无血管视网膜进行血管造影引导激光治疗后出现再灌注。抗血管内皮生长因子治疗可减少新生血管形成并促进视网膜血管生长。对无血管视网膜进行IVB和FA引导激光治疗是IP的一种治疗选择。[《眼科手术、激光与视网膜成像》。2019；50：e33 - e37。]
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