Silvestri Valeria, Sapienza Paolo, Ossola Paolo, Grande Raffaele, Brachini Gioia, Sterpetti Antonio V, Mingoli Andrea
Department of Surgery "Pietro Valdoni", "Sapienza" University of Rome, Rome, Italy.
Department of Surgery "Pietro Valdoni", "Sapienza" University of Rome, Rome, Italy.
Ann Vasc Surg. 2019 Jul;58:384.e5-384.e8. doi: 10.1016/j.avsg.2018.11.030. Epub 2019 Feb 13.
Visceral aneurysms are rare entities, with a reported incidence of 0.01-2%. Fibromuscular dysplasia is a nonatherosclerotic, noninflammatory artery disease, which may predispose to aneurysmal degeneration. Schizophrenia has been linked to an increased cardiovascular risk because of the influence of traditional and disease-specific risk factors. We report the case of a 44-year-old male schizophrenic patient presenting with a ruptured giant aneurysm of superior mesenteric artery, managed by mesenteric ligation. The histologic diagnosis was fibromuscular dysplasia. Another case of visceral aneurysm in schizophrenic patient with similar histologic features has been previously reported in literature.
内脏动脉瘤是罕见的疾病，报告发病率为0.01%-2%。纤维肌性发育异常是一种非动脉粥样硬化、非炎症性动脉疾病，可能易导致动脉瘤样退变。由于传统和疾病特异性危险因素的影响，精神分裂症与心血管风险增加有关。我们报告一例44岁男性精神分裂症患者，其表现为肠系膜上动脉巨大动脉瘤破裂，通过肠系膜结扎进行治疗。组织学诊断为纤维肌性发育异常。先前文献中曾报道过另一例具有相似组织学特征的精神分裂症患者内脏动脉瘤病例。
