Unit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, 35131 Padova, Italy.
Pediatric Intermediate Care Unit, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Nutrients. 2019 Feb 14;11(2):400. doi: 10.3390/nu11020400.
The present research combines real data and parameters found in recent literature that were used to design realistic scenarios demonstrating the potential effects (benefits and costs) of the World Health Organization (WHO)'s risk communication regarding the consumption of processed meat, which was proven to be associated with an increased risk of colorectal cancer (CRC) in an International Agency for Research on Cancer (IARC)/WHO report. The impact of the risk communication of processed meat consumption was simulated using Monte Carlo microsimulation models. The results showed that a 1% reduction in the number of high-level processed meat consumers may lead to a yearly decrease in CRC cases of 406.43 (IC 95%: -243.94, 1056.81), while the more extreme scenario of a 15% reduction may lead to 2086.62 fewer cases (IC 95%: 1426.66, 2746.57). On the other hand, if demand contraction in the processed meat sector resulted in a 0.1% loss in employment, one could expect 27.23 all-cause mortalities attributable to job loss (IC 95%: 16.55, 37.80). This simulation study demonstrates that caution should be taken when implementing public awareness campaigns, particularly when the prevention message is not straightforward.
本研究结合了真实数据和最近文献中发现的参数,用于设计现实场景,以展示世界卫生组织(WHO)关于食用加工肉类风险沟通的潜在影响(收益和成本),该研究报告已证明食用加工肉类与结直肠癌(CRC)风险增加有关。使用蒙特卡罗微模拟模型模拟了食用加工肉类风险沟通的影响。结果表明,减少 1%高水平食用加工肉类消费者的数量可能导致每年 CRC 病例减少 406.43 例(95%CI:-243.94,1056.81),而更极端的减少 15%的情况下可能导致 2086.62 例 CRC 病例减少(95%CI:1426.66,2746.57)。另一方面,如果加工肉类行业的需求收缩导致 0.1%的就业损失,则可能有 27.23 例全因死亡归因于失业(95%CI:16.55,37.80)。这项模拟研究表明,在实施公众意识运动时应谨慎行事,特别是当预防信息不明确时。