在首次发生心血管事件之前的血脂控制及相关危险因素。

Lipid control and associated risk factors, before suffering from the first cardiovascular event.

作者信息

Oriol Torón Pilar Ángeles, Badía Farré Teresa, Romaguera Lliso Amparo

机构信息

Medicina Familiar y Comunitaria, ABS Martorell, SAP Alt Penedès-Garraf-Baix Llobregat Nord, DAP Costa de Ponent, Institut Català de la Salut, Barcelona, España.

出版信息

Clin Investig Arterioscler. 2019 Jul-Aug;31(4):141-151. doi: 10.1016/j.arteri.2018.12.002. Epub 2019 Feb 12.

DOI:10.1016/j.arteri.2018.12.002

PMID:30770220

Abstract

OBJECTIVE

To ascertain the degree of lipidic control before the first cardiovascular accident in population attended during 2013 at Primary Care. To analyze the distribution of these events depending on control intervals of cholesterol LDL (LDL-chol), cholesterol HDL (HDL-chol) and triglycerides (TG).

METHOD

A multicentric cross-sectional, descriptive study on above 18-year-old people attended at the centres of the Primari Care Service (PCS) Baix Llobregat Nord, who had suffered a first cardiac or cerebral ischemic attack from 01/01/2013 to 31/12/2013. Variables collected included age,sex, smoking, high blood preassure,diabetes, dyslipidemia (DLP), obesity, total cholesterol (chol-tot), LDL-chol, HDL-chol, TG, systolic and diastolic blood preassure (SBP,DBP), IMC, HbA1c, atherogenic indices, REGICOR, drugs.

RESULTS

379 affected people, among them 197 (52%) heart attack and 182 (48%) stroke (ictus). Two hundred and twenty-five (54.4%) males, diagnosis median age 68.9 years (DS 13.7), 71.2 (DS 14.4) in CV (p: .001). High blood preassure 214 (56.5%), diabetes 113 (29.8%), DLP 193 (50.9%). Cases in LDL<100-159: 88%, HDL≥40/50: 72.8%, TG<150: 71.3%. chol-tot average: 198.3 mg/dl (DS 40.2), LDL-chol:121 (DS 33.8), LDL-chol<130:170 (58.6%). HDL-chol average: 52.5 mg/dl (DS 15.4) and TG: 130.9 mg/dl (DS 73.2) (CI:139.5 [DS 84.2] vs. CV: 120.9 [DS 55.9] [p: .003]). Optimal chol-tot/HDL-chol 67%, optimal TG/HDL-chol 39.8%. CI:optimal chol-tot/HDL-chol male vs. female: 51.2% vs. 76.9% (p: .002); optimal TG/HDL-chol male vs. female: 28% vs. 53.8% (p: .004).

CONCLUSIONS

The quantity of events was similar in both cardiac and cerebral territories, whereas the median age in the diagnosis was a little higher in CV. High blood preassure, DLP and obesity are the most prevalent FRCV, and its control at primary prevention is improvable. Most of the cases were grouped in the LDL lipid ranges <100-159mg/dl, HDL ≥ 40/50mg/dl and TG <150mg/dl.

摘要

目的

确定2013年在基层医疗就诊的人群首次发生心血管意外之前的血脂控制程度。根据低密度脂蛋白胆固醇（LDL-chol）、高密度脂蛋白胆固醇（HDL-chol）和甘油三酯（TG）的控制区间分析这些事件的分布情况。

方法

对2013年1月1日至2013年12月31日期间在baix Llobregat Nord初级医疗服务中心就诊的18岁以上首次发生心脏或脑缺血性发作的患者进行多中心横断面描述性研究。收集的变量包括年龄、性别、吸烟、高血压、糖尿病、血脂异常（DLP）、肥胖、总胆固醇（chol-tot）、LDL-chol、HDL-chol、TG、收缩压和舒张压（SBP、DBP）、体质指数（IMC）、糖化血红蛋白（HbA1c）、致动脉粥样硬化指数、REGICOR、药物。

结果

379名患者，其中197例（52%）为心脏病发作，182例（48%）为中风（卒中）。225名（54.4%）男性，诊断中位年龄68.9岁（标准差13.7），心血管疾病患者中为71.2岁（标准差14.4）（p：0.001）。高血压患者214例（56.5%），糖尿病患者113例（29.8%），血脂异常患者193例（50.9%）。LDL<100 - 159的病例占88%，HDL≥40/50的病例占72.8%，TG<150的病例占71.3%。总胆固醇平均为198.3mg/dl（标准差40.2），LDL-chol为121（标准差33.8），LDL-chol<130的有170例（58.6%）。HDL-chol平均为52.5mg/dl（标准差15.4），TG为130.9mg/dl（标准差73.2）（置信区间：139.