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老年慢性肾脏病患者的糖尿病管理。

Diabetes Management in Older Adults With Chronic Kidney Disease.

机构信息

Department of Medicine, Division of Endocrinology, Western University, London, Ontario, Canada.

Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada.

出版信息

Curr Diab Rep. 2019 Feb 15;19(3):11. doi: 10.1007/s11892-019-1128-3.

DOI:10.1007/s11892-019-1128-3
PMID:30771017
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6469508/
Abstract

PURPOSE OF REVIEW

Older adults often live with chronic disease including diabetes and its complications. In this review, we examine the complexity and heterogeneity of older adults with diabetes and chronic kidney disease, explore the nuances in their diabetes-related monitoring, and discuss their best diabetes management.

RECENT FINDINGS

Although there remains an overall lack of studies in older adults with diabetes and chronic kidney disease, recent reports have highlighted their vulnerabilities. These individuals face an increased risk of cognitive impairment and dementia, frailty, dysglycemia, polypharmacy, declining kidney function, and acute kidney injury. Their diabetes management should focus upon safer antihyperglycemic medications, close monitoring, and care individualization. Older adults with diabetes and chronic kidney disease are a complex population who requires careful diabetes management and monitoring. Research efforts might focus on improving the care and outcomes of these patients.

摘要

目的综述

老年人常患有慢性疾病,包括糖尿病及其并发症。在本次综述中,我们探讨了患有糖尿病和慢性肾脏病的老年人的复杂性和异质性,研究了他们在糖尿病相关监测方面的细微差别,并讨论了他们的最佳糖尿病管理方法。

最新发现

尽管目前针对患有糖尿病和慢性肾脏病的老年人的研究仍相对较少,但最近的报告强调了他们的脆弱性。这些个体面临着认知障碍和痴呆、虚弱、血糖异常、多种药物治疗、肾功能下降和急性肾损伤的风险增加。他们的糖尿病管理应侧重于更安全的降糖药物、密切监测和个体化护理。患有糖尿病和慢性肾脏病的老年人是一个复杂的群体,需要对其进行仔细的糖尿病管理和监测。研究工作可能侧重于改善这些患者的护理和结局。

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本文引用的文献

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The Health and Health Care of Adults With Type 1 And 2 Diabetes Across the Spectrum of Estimated Glomerular Filtration Rates.1 型和 2 型糖尿病患者在估计肾小球滤过率谱中的健康和医疗保健。
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Physical frailty and cognitive impairment is associated with diabetes and adversely impact functional status and mortality.身体虚弱和认知障碍与糖尿病有关,并对功能状态和死亡率产生不利影响。
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