Salinas J A
Biomed Environ Sci. 1988 Dec;1(4):392-405.
Over the past two decades, industrialized nations have addressed and attempted to solve the problems of chemical risk through the development of laws, government and private organizations, and specialized manpower. Developing nations are now recognizing that the presence of toxicants in the environment, foods, consumer products, and the workplace can seriously affect human health, the ecology, international relations, and economic activities such as trade and tourism. The design and implementation of regulatory programs in developing countries is hampered by lack of government and public concern, pressure of more urgent needs, vested interests of industry, and lack of adequately trained professionals. These factors have allowed developed nations to sell abroad drugs, pesticides, and other chemicals considered too hazardous for use in their own countries. Conversely, products from developing nations must comply with rigorous standards for acceptance by developed nations. Some of these problems would be lessened by agreement on international chemical control guidelines. Multilateral availability of complete information about chemicals is essential. The coordination of this effort should be in the hands of international organizations and reinforced by bilateral agreements between countries. Appropriate public education and economic incentives at the national level would help in enforcing regulatory toxicology.
在过去二十年中,工业化国家已通过制定法律、政府及私人组织以及专业人力来应对并试图解决化学风险问题。发展中国家如今正认识到,环境、食品、消费品及工作场所中有毒物质的存在会严重影响人类健康、生态、国际关系以及贸易和旅游等经济活动。发展中国家监管项目的设计与实施受到诸多因素阻碍,包括政府和公众关注度不足、更紧迫需求的压力、行业既得利益以及缺乏训练有素的专业人员。这些因素使得发达国家得以向国外销售在其本国被认为过于危险而禁止使用的药品、农药及其他化学品。相反,发展中国家的产品要想被发达国家接受,就必须符合严格标准。就国际化学品控制准则达成一致将减轻其中一些问题。化学品完整信息的多边共享至关重要。这项工作的协调应由国际组织负责,并通过国家间的双边协议予以加强。在国家层面开展适当的公众教育和提供经济激励措施将有助于实施监管毒理学。