Kang Z, Yang H
Xiamen Pediatric Hospital Affiliated to Fudan University, Xiamen Children's Hospital, Xiamen 361000, China.
Zhonghua Yan Ke Za Zhi. 2019 Feb 11;55(2):111-114. doi: 10.3760/cma.j.issn.0412-4081.2019.02.008.
To estimate the choroidal thickness (CT) in healthy children aged 2-6 years old and its relation to axial length, age and gender. Cross-sectional study. CT was assessed using spectral domain optical coherence tomography (OCT) in 126 children aged 2 to 6 years. CT was measured at nine locations, including the subfovea and 1 mm and 3 mm nasal, temporal, superior and inferior to the fovea. Mean subfoveal choroidal thickness (SFCT) was 331.56±62.03 μm. The choroid was thickest at the subfoveal and 1 mm temporal area, and thinner nasally compared to temporally, superiorly and inferiorly. No statistical significance of SFCT between male and female was noted. Stepwise multiple regression analysis revealed that axial length and age were associated significantly with SFCT (0.00), while there was no detectable effect of sex on SFCT (0.94). Choroidal thickness was negatively correlated to axial length and positively correlated to age in preschool children. The development of the choroid in early childhood offset the effect of the expansion of eyes. Gender played a minor role in the choroidal development in early childhood. .
评估2至6岁健康儿童的脉络膜厚度（CT）及其与眼轴长度、年龄和性别的关系。横断面研究。使用光谱域光学相干断层扫描（OCT）对126名2至6岁儿童的CT进行评估。在九个位置测量CT，包括黄斑中心凹下以及黄斑中心凹鼻侧、颞侧、上方和下方1毫米及3毫米处。平均黄斑中心凹下脉络膜厚度（SFCT）为331.56±62.03μm。脉络膜在黄斑中心凹下和颞侧1毫米区域最厚，鼻侧比颞侧、上方和下方薄。未发现男女之间SFCT有统计学差异。逐步多元回归分析显示，眼轴长度和年龄与SFCT显著相关（P = 0.00），而性别对SFCT无显著影响（P = 0.94）。学龄前儿童的脉络膜厚度与眼轴长度呈负相关，与年龄呈正相关。幼儿期脉络膜的发育抵消了眼球扩张的影响。性别在幼儿期脉络膜发育中起次要作用。
