Clinic of Nuclear Medicine, Jena University Hospital, Jena, Germany.
Clinic of Nuclear Medicine, Jena University Hospital, Jena, Germany.
Ultrasound Med Biol. 2019 May;45(5):1243-1252. doi: 10.1016/j.ultrasmedbio.2019.01.003. Epub 2019 Feb 14.
Side-by-side evaluation of thyroid ultrasound (US) and TcO scintigraphy can lead to uncertainties in the correct topographic assignment of thyroid nodules. The aim of this study was to evaluate TcO single-photon emission computed tomography/ultrasound (SPECT/US) fusion imaging. Seventy-nine patients were prospectively investigated. If conventional diagnostics of the thyroid gland (B-mode-US, scintigraphy) produced unclear findings, SPECT was performed and transferred to a US device for real-time sensor-navigated 3-D fusion US investigation. The data sets were manually matched according to their contours. Finally, SPECT/US versus conventional diagnostics was rated using an ordinal 4-point scale (SPECT/US >> conventional diagnostics, SPECT/US > conventional diagnostics, SPECT/US = conventional diagnostics, SPECT/US < conventional diagnostics). SPECT/US was superior (>>, >) in 84% and equivalent (=) in 16% of the cases, respectively. No statistically significant differences were observed for uni-, bi- and multinodular goiters (p ≥ 0.3). In 67%, the respective problem that arose after conventional diagnostics was clarified by SPECT/US. SPECT/US was feasible and was helpful for the clarification of uncertain functionality assessments of thyroid nodules.
甲状腺超声（US）与 TcO 闪烁显像的并排评估可能导致甲状腺结节的正确定位出现不确定。本研究旨在评估 TcO 单光子发射计算机断层扫描/超声（SPECT/US）融合成像。79 例患者前瞻性研究。如果甲状腺的常规诊断（B 型超声、闪烁显像）结果不明确，则进行 SPECT 检查，并将其传输到超声设备上进行实时传感器导航 3D 融合超声检查。根据轮廓手动匹配数据集。最后，使用序数 4 分制（SPECT/US＞常规诊断，SPECT/US＞常规诊断，SPECT/US＝常规诊断，SPECT/US＜常规诊断）对 SPECT/US 与常规诊断进行评分。SPECT/US 在 84%的病例中（>>、>）优于（优于、优于），在 16%的病例中（=）相当于常规诊断。单、双和多结节性甲状腺肿（p≥0.3）之间未观察到统计学差异。在 67%的情况下，SPECT/US 澄清了常规诊断后出现的相应问题。SPECT/US 是可行的，并有助于澄清甲状腺结节功能评估的不确定性。
