Scott Jonathan M, Lindsey Andrea T, Costello Rebecca B, Deuster Patricia A
Assistant Professor at the Uniformed Services University.
Director of Operation Supplement Safety, a program of the Consortium for Health and Military Performance (CHAMP).
Nutr Today. 2018 Sep-Oct;53(5):229-233. doi: 10.1097/NT.0000000000000295.
Over half of young adults, athletes, and Military Service Members self-report using at least one dietary supplement (DS) 1 or more times per week. DS may be consumed to improve health, provide more energy, increase muscle strength, and/or enhance performance. The United States Food and Drug Administration (FDA) has raised concerns regarding adulteration, safety, and adverse events associated with DS marketed for brain health and bodybuilding. Some DS products may compromise health as well as lead to a serious adverse event. The National Institutes of Health (NIH) Dietary Supplement Label Database (DSLD), available at https://dsld.nlm.nih.gov/, can be freely accessed and used by researchers, providers, and consumers alike to screen for potentially harmful DS. It was developed to serve the research community and as a resource for health care providers and the public. Herein we provide two examples of how the database can be used to identify DS ingredients of concern in products marketed for brain health and bodybuilding. The search for DS marketed for brain health returned 49 unique DS, and the search on DS marketed for bodybuilding returned 18 unique DS. Search results were cross-referenced with the Operation Supplement Safety High-Risk Supplement List, the FDA Tainted Products Marketed as Dietary Supplements list, the Natural Medicines database, and NIH Office of Dietary Supplements Fact Sheets. Three ingredients found in DS marketed for brain health and two ingredients in DS marketed for bodybuilding were identified as "of concern". Educational tools, including the DSLD, can help consumers and providers make informed decisions regarding DS.
超过半数的年轻人、运动员和军人自我报告称每周至少使用一种膳食补充剂（DS）一次或多次。人们使用DS可能是为了改善健康、提供更多能量、增强肌肉力量和/或提高运动表现。美国食品药品监督管理局（FDA）对用于脑健康和健美市场的DS的掺假、安全性及不良事件表示担忧。一些DS产品可能损害健康并导致严重不良事件。国立卫生研究院（NIH）的膳食补充剂标签数据库（DSLD）可在https://dsld.nlm.nih.gov/上免费获取，研究人员、医疗服务提供者和消费者均可自由访问和使用，以筛查潜在有害的DS。该数据库是为服务研究界而开发的，也是医疗服务提供者和公众的一个资源。在此，我们提供两个例子，说明如何利用该数据库识别用于脑健康和健美市场的产品中令人担忧的DS成分。搜索用于脑健康的DS返回了49种独特的DS，搜索用于健美的DS返回了18种独特的DS。搜索结果与“补充剂安全行动高风险补充剂清单”、FDA列为膳食补充剂的受污染产品清单、天然药物数据库以及NIH膳食补充剂办公室情况说明书进行了交叉参考。在用于脑健康的DS中发现的三种成分以及用于健美的DS中的两种成分被确定为“令人担忧的成分”。包括DSLD在内的教育工具可以帮助消费者和医疗服务提供者就DS做出明智的决策。
