胆结石患者心血管风险评估：一项描述性横断面研究。

Evaluation of the cardiovascular risk in patients with biliary stones: a descriptive cross-sectional study.

作者信息

Seddighi Shermin, Ghidari Mohammad Esmaiel, Sadeghi Amir, Shahrbaf Mohammad Amin, Mahmanzar Mohammad Amin, Saadati Saeede, Yari Zahra

机构信息

Department of Cardiology, Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Gastroenterol Hepatol Bed Bench. 2018 Winter;11(Suppl 1):S14-S19.

PMID:30774802

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6348000/

Abstract

AIM

the aim of this study was evaluating the risk of cardiovascular disease in patients with gallstones.

BACKGROUND

Gallstones is the most common Biliary System disorder which its prevalence is increasing. On other hand, cardiovascular disease is the most common cause of mortality in the world. The causes and risk factors of cardiovascular diseases and gallstones are in common.

METHODS

In this descriptive cross-sectional study, patient with gallstones who hospitalized in Taleghani Hospital of Shahid Beheshti University of medical sciences or referred to its clinics in 2017, shared their demographic information and their underlying diseases with us. In addition, more data was collected with clinical examination, blood test, echocardiography and ultrasonography. Data was analyzed by SPSS vs21 software. In addition, online software was used for calculating Framingham and ASCVD risk score for cardiovascular diseases.

RESULTS

105 patients with gallstones and 105 healthy people participated in this study. There was no significant difference between these two groups for existence of main risk factors, but the average amount of ALT, AST, and ALP enzymes in patients with gallstones were significantly more than the control group (P value<0.05). The average amount of Framingham score was not significantly different between these two groups and the average score of ASCVD was statistically lower in our case group.

CONCLUSION

The risk of cardiovascular disease in patients with gallstones is not significantly more than the general population.

摘要

目的

本研究旨在评估胆结石患者患心血管疾病的风险。

背景

胆结石是最常见的胆道系统疾病，其患病率正在上升。另一方面，心血管疾病是全球最常见的死亡原因。心血管疾病和胆结石的病因及危险因素有共同之处。

方法

在这项描述性横断面研究中，2017年在沙希德·贝赫什提医科大学塔莱加尼医院住院或到其诊所就诊的胆结石患者与我们分享了他们的人口统计学信息和基础疾病。此外，通过临床检查、血液检查、超声心动图和超声检查收集了更多数据。数据用SPSS vs21软件进行分析。此外，使用在线软件计算心血管疾病的弗雷明汉和动脉粥样硬化性心血管疾病（ASCVD）风险评分。