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一头死产犊牛同时感染牛病毒性腹泻病毒1型和2型：组织分布及分子特征

Dual natural infection with bovine viral diarrhea virus -1 and -2 in a stillborn calf: tissue distribution and molecular characterization.

作者信息

Spetter Maximiliano J, Uriarte Enrique L Louge, Altamiranda Erika A González, Leunda María R, Pereyra Susana B, Verna Andrea E, Odeón Anselmo C

机构信息

Fondo para la Investigación Científica y Tecnológica (FONCYT), Godoy Cruz 2370 2° piso, Buenos Aires (C1425FQD), Argentina.

Grupo de Sanidad Animal, Área de Producción Animal, INTA EEA Balcarce, Ruta 226, km 73.5 (CP 7620), Argentina.

出版信息

Open Vet J. 2018;8(4):493-497. doi: 10.4314/ovj.v8i4.23. Epub 2018 Dec 31.

DOI:10.4314/ovj.v8i4.23
PMID:30775291
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6356097/
Abstract

Dual infections with both bovine viral diarrhea virus (BVDV)-1 and -2 seem to be unusual. The aim of this study was to describe an infection with both BVDV genotypes in a stillborn calf. Virus isolation and phylogenetic analyses of the 5´UTR and NS5B regions confirmed the presence of BVDV-1b and -2b in spleen and lung, whereas BVDV-2b was also detected in brain, heart, liver, kidney and, fluid of cavities. These results confirm that dual infections with both BVDV-1 and BVDV-2 species can occur naturally and their tissue distribution can be different.

摘要

牛病毒性腹泻病毒（BVDV）-1型和-2型的双重感染似乎并不常见。本研究的目的是描述一头死产犊牛感染这两种BVDV基因型的情况。对5´非翻译区（UTR）和NS5B区域进行病毒分离和系统发育分析，证实脾脏和肺中存在BVDV-1b和-2b，而在脑、心脏、肝脏、肾脏和体腔液中也检测到了BVDV-2b。这些结果证实，BVDV-1型和BVDV-2型的双重感染可自然发生，且它们的组织分布可能有所不同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77c0/6356097/86ad1bba2ad1/OpenVetJ-8-493-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77c0/6356097/86ad1bba2ad1/OpenVetJ-8-493-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77c0/6356097/86ad1bba2ad1/OpenVetJ-8-493-g001.jpg

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