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一例Rhupus(类风湿性关节炎与系统性红斑狼疮重叠综合征)——罕见病例报告

A Case of Rhupus-reporting of a Rare Entity.

作者信息

Sinha Preema, Singhal Anuj, Bhattacharjee Saikat, Oberoi Bhavni

机构信息

Department of Dermatology, Armed Forces Medical College, Pune, Maharashtra, India.

出版信息

Indian Dermatol Online J. 2019 Jan-Feb;10(1):58-60. doi: 10.4103/idoj.IDOJ_55_18.

Abstract

Rhupus syndrome, a rare entity, is the co-existence of systemic lupus erythematosus (SLE) with rheumatoid arthritis (RA). It manifests as more RA and less SLE related damages. The duration of the disease is longer than typical RA or SLE. Controversies exist regarding the definition of Rhupus. The incidence of Rhupus in patients with arthritis is 0.01%-0.2% and <2% in patients with connective tissue diseases. However, we report a rare case of rhupus in a 55-year-old lady with polyarthritis and joint deformities of 6 year duration, presenting with features of lupus erythematosus.

摘要

类风湿性关节炎-系统性红斑狼疮综合征是一种罕见的病症,它是系统性红斑狼疮(SLE)与类风湿性关节炎(RA)并存的情况。其表现为类风湿性关节炎相关损害较多,而系统性红斑狼疮相关损害较少。该疾病的病程比典型的类风湿性关节炎或系统性红斑狼疮更长。关于类风湿性关节炎-系统性红斑狼疮综合征的定义存在争议。关节炎患者中类风湿性关节炎-系统性红斑狼疮综合征的发病率为0.01%-0.2%,结缔组织病患者中的发病率<2%。然而,我们报告了一例罕见的类风湿性关节炎-系统性红斑狼疮综合征病例,患者为一名55岁女性,患有多关节炎且关节畸形已有6年,同时伴有红斑狼疮的特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf6c/6362750/9aab303bad45/IDOJ-10-58-g001.jpg

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