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李斯特菌病导致的晚期死产

Late stillbirth due to listeriosis.

作者信息

Segado-Arenas Antonio, Atienza-Cuevas Lidia, Broullón-Molanes José Roman, Rodríguez-González Moisés, Lubián-López Simón Pedro

机构信息

Hospital Universitário Puerta del Mar, Department of Pediatrics, Division of Neonatology. Cádiz, Spain.

Hospital Universitário Puerta del Mar, Department of Pathological Anatomy. Cádiz, Spain.

出版信息

Autops Case Rep. 2018 Oct 22;8(4):e2018051. doi: 10.4322/acr.2018.051. eCollection 2018 Oct-Dec.

Abstract

Listeriosis is a sporadic infectious disease, which affects high-risk populations, such as the elderly, pregnant women, newborns, and immunocompromised patients. During pregnancy, listeriosis usually presents like a mild non-specific infection, but it may be responsible for fetal loss, preterm labor, early onset neonatal sepsis, and neonatal death. We report the case of a late stillbirth secondary to maternal chorioamnionitis. was isolated from the amniotic fluid and the fetal pleural fluid. The fetal autopsy revealed a disseminated inflammatory response with multi-organ involvement. This case illustrates the importance of the prevention and the diagnosis of listeriosis during gestation and may help us to understand the physiopathology of fetal loss due to listeriosis.

摘要

李斯特菌病是一种散发性传染病,影响高危人群,如老年人、孕妇、新生儿和免疫功能低下的患者。在怀孕期间,李斯特菌病通常表现为轻度非特异性感染,但它可能导致胎儿丢失、早产、早发型新生儿败血症和新生儿死亡。我们报告一例因母体绒毛膜羊膜炎导致的晚期死产病例。从羊水和胎儿胸腔积液中分离出了[具体病菌名称未给出]。胎儿尸检显示有弥漫性炎症反应,累及多个器官。该病例说明了孕期预防和诊断李斯特菌病的重要性,并可能有助于我们了解李斯特菌病导致胎儿丢失的病理生理过程。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66c0/6360831/17b2881da849/autopsy-08-04e2018051-g01.jpg

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