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憩室炎所致具肝肺脓肿的坏死梭杆菌败血症

Fusobacterium Septicemia with Liver and Lung Abscesses Due to Diverticulitis.

作者信息

Sharma Akshay, Goyal Sachin, Arsene Camelia, Krishnamoorthy Geetha, Ehrinpreis Murray

机构信息

Department of Internal Medicine, Sinai Grace Hospital, Detroit Medical Center/Wayne State University, Detroit, MI.

Department of Internal Medicine, Division of Gastroenterology, Detroit Medical Center/Wayne State University, Detroit, MI.

出版信息

ACG Case Rep J. 2018 Dec 19;5:e99. doi: 10.14309/crj.2018.99. eCollection 2018.

DOI:10.14309/crj.2018.99
PMID:30775398
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6358581/
Abstract

The species is known for its association with septic thrombophlebitis of the internal jugular vein (Lemierre's syndrome). Lemierre's syndrome is associated with septic emboli to the liver and lungs, often causing multiple abscesses. We present a unique case of septicemia in which the bacteria invaded the portal vein through the gastrointestinal mucosa due to diverticulitis and spread hematogenously to the liver and lungs, causing abscesses. It was treated successfully with 6 weeks of antibiotics. Physicians should be aware of this rare pathogen and suspect its presence in severe pharyngitis or culture-negative liver abscess.

摘要

该物种以内颈静脉化脓性血栓性静脉炎(勒米尔综合征)而闻名。勒米尔综合征与肝脏和肺部的脓毒性栓子有关,常导致多发性脓肿。我们报告了一例独特的败血症病例,细菌因憩室炎通过胃肠道黏膜侵入门静脉,并经血行扩散至肝脏和肺部,引起脓肿。经6周抗生素治疗后成功治愈。医生应了解这种罕见病原体,并怀疑其在严重咽炎或培养阴性的肝脓肿中存在。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7030/6358581/19647c7e0343/CG-CGCR180087F003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7030/6358581/7e2f5bb98842/CG-CGCR180087F001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7030/6358581/d03980132857/CG-CGCR180087F002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7030/6358581/19647c7e0343/CG-CGCR180087F003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7030/6358581/7e2f5bb98842/CG-CGCR180087F001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7030/6358581/d03980132857/CG-CGCR180087F002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7030/6358581/19647c7e0343/CG-CGCR180087F003.jpg

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引用本文的文献

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Pylephlebitis Complicated by Hepatic Abscesses due to : A Case of Lemierre's Syndrome Variant and Literature Review.因……导致的门静脉炎合并肝脓肿:1例勒米尔综合征变异型病例及文献综述
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本文引用的文献

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Gastroenterology. 2018 Aug;155(2):383-390.e8. doi: 10.1053/j.gastro.2018.04.028. Epub 2018 May 3.
2
Lemierre's syndrome variant of the gut.肠道型勒米尔综合征变异型
BMJ Case Rep. 2017 Oct 20;2017:bcr-2017-221567. doi: 10.1136/bcr-2017-221567.
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Bacteraemia and liver abscess due to .由……引起的菌血症和肝脓肿。 (你提供的原文不完整,缺少具体病因)
BMJ Case Rep. 2017 Jul 27;2017:bcr-2017-220654. doi: 10.1136/bcr-2017-220654.
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Lemierre's syndrome: current perspectives on diagnosis and management.勒米尔综合征:诊断与管理的当前观点
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The clinical presentation of Fusobacterium-positive and streptococcal-positive pharyngitis in a university health clinic: a cross-sectional study.在大学健康诊所中,梭杆菌阳性和链球菌阳性咽炎的临床表现:一项横断面研究。
Ann Intern Med. 2015 Feb 17;162(4):241-7. doi: 10.7326/M14-1305.
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Incidence, risk factors, and outcomes of Fusobacterium species bacteremia.梭杆菌属菌血症的发生率、危险因素和结局。
BMC Infect Dis. 2013 Jun 5;13:264. doi: 10.1186/1471-2334-13-264.
7
[Case of Fusobacterium necrophorum sepsis (Lemierre's syndrome) with pulmonary septic emboli and liver abscess].[坏死梭杆菌败血症(勒米尔综合征)合并肺脓毒性栓子和肝脓肿病例]
Nihon Rinsho Meneki Gakkai Kaishi. 2011;34(5):431-7. doi: 10.2177/jsci.34.431.
8
Lemierre's syndrome: A systematic review.勒米尔综合征:一项系统评价。
Laryngoscope. 2009 Aug;119(8):1552-9. doi: 10.1002/lary.20542.
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Fusobacterial infections: clinical spectrum and incidence of invasive disease.梭杆菌感染:侵袭性疾病的临床谱及发病率
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Fusobacterium: elusive cause of life-threatening septic thromboembolism.梭杆菌:危及生命的感染性血栓栓塞的隐匿病因。
Can Fam Physician. 2007 Sep;53(9):1451-3.