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由咽峡炎链球菌引起的勒米尔综合征:一例报告及文献复习

Lemierre's Syndrome Due to Streptococcus anginosus: A Case Report and Review of the Literature.

作者信息

Jena Nihar, Yella Prashanth Reddy, Chandramohan Deepak

机构信息

Cardiovascular Medicine, Saint Joseph Mercy Oakland, Pontiac, USA.

Internal Medicine/Hospital Medicine, Yuma Regional Medical Center, Yuma, USA.

出版信息

Cureus. 2023 Aug 29;15(8):e44311. doi: 10.7759/cureus.44311. eCollection 2023 Aug.

DOI:10.7759/cureus.44311
PMID:37779762
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10535718/
Abstract

Lemierre's syndrome, also known as anaerobic post-anginal septicemia, necrobacillosis, and the "forgotten disease," is a rare manifestation. It is often presented with sepsis, sore throat, fever, neck pain, internal jugular vein thrombophlebitis/thrombosis, and septic emboli. The bacteria that are usually associated with the disease are species, but it is also associated with , , and other bacterial species. The diagnosis of Lemierre's syndrome is made based on evidence of septic thrombophlebitis, preceding oropharyngeal infection, and positive culture. Treatment usually consists of antibiotics directed toward the causative organism. The use of anticoagulation, although controversial, is shown to be beneficial by several studies. We describe a middle-aged patient who presented with a sore throat, neck pain, and dysphagia. Imaging of the neck and chest revealed right jugular thrombosis along with septic emboli in the lungs. The culture of the blood and pus drained from the peritonsillar abscess grew . In this study, we have illustrated the effective management of Lemierre's syndrome with antibiotics, anticoagulants, and needle aspiration of abscess.

摘要

勒米尔综合征,也被称为厌氧性咽后败血症、坏死杆菌病以及“被遗忘的疾病”,是一种罕见的病症。它常表现为败血症、咽喉痛、发热、颈部疼痛、颈内静脉血栓性静脉炎/血栓形成以及脓毒性栓子。通常与该疾病相关的细菌是 菌属,但它也与 菌、 菌及其他细菌种类有关。勒米尔综合征的诊断基于血栓性静脉炎、先前的口咽感染证据以及阳性培养结果。治疗通常包括针对致病微生物的抗生素治疗。抗凝治疗的使用虽然存在争议,但多项研究表明其有益。我们描述了一名中年患者,其表现为咽喉痛、颈部疼痛和吞咽困难。颈部和胸部影像学检查显示右颈静脉血栓形成以及肺部脓毒性栓子。从扁桃体周围脓肿引流的血液和脓液培养出 菌。在本研究中,我们阐述了使用抗生素、抗凝剂以及脓肿穿刺抽吸对勒米尔综合征进行有效管理的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa8e/10535718/21d681119f0d/cureus-0015-00000044311-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa8e/10535718/c79c4ae69cf1/cureus-0015-00000044311-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa8e/10535718/05aeb565c3e1/cureus-0015-00000044311-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa8e/10535718/2ccf7733395f/cureus-0015-00000044311-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa8e/10535718/21d681119f0d/cureus-0015-00000044311-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa8e/10535718/c79c4ae69cf1/cureus-0015-00000044311-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa8e/10535718/05aeb565c3e1/cureus-0015-00000044311-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa8e/10535718/2ccf7733395f/cureus-0015-00000044311-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa8e/10535718/21d681119f0d/cureus-0015-00000044311-i04.jpg

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本文引用的文献

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Oesophageal cancer presenting as Lemierre's syndrome caused by .表现为勒米耶综合征的食管癌由……引起 。 (原英文文本似乎不完整)
BMJ Case Rep. 2017 Apr 17;2017:bcr-2017-219661. doi: 10.1136/bcr-2017-219661.
2
Lemierre Syndrome: A Retrospective Study of the Role of Anticoagulation and Thrombosis Outcomes.勒米尔综合征:抗凝作用及血栓形成结局的回顾性研究
Acta Haematol. 2017;137(2):59-65. doi: 10.1159/000452855. Epub 2016 Dec 23.
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Lemierre's syndrome: current perspectives on diagnosis and management.勒米尔综合征:诊断与管理的当前观点
Infect Drug Resist. 2016 Sep 14;9:221-227. doi: 10.2147/IDR.S95050. eCollection 2016.
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To anticoagulate? Controversy in the management of thrombotic complications of head & neck infections.进行抗凝治疗?头颈部感染血栓性并发症管理中的争议。
Int J Pediatr Otorhinolaryngol. 2016 Sep;88:129-35. doi: 10.1016/j.ijporl.2016.06.013. Epub 2016 Jun 6.
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Lemierre syndrome: early recognition and management.勒米尔综合征:早期识别与处理
CMAJ. 2015 Nov 3;187(16):1229-1231. doi: 10.1503/cmaj.150476. Epub 2015 Aug 10.
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Lemierre's syndrome.勒米尔综合征
Int J Emerg Med. 2013 Oct 23;6(1):40. doi: 10.1186/1865-1380-6-40.
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Lemierre's syndrome: A systematic review.勒米尔综合征:一项系统评价。
Laryngoscope. 2009 Aug;119(8):1552-9. doi: 10.1002/lary.20542.
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Lemierre's syndrome: more than a historical curiosa.勒米尔综合征:不止是历史趣闻。
Postgrad Med J. 2004 Jun;80(944):328-34. doi: 10.1136/pgmj.2003.014274.
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The evolution of Lemierre syndrome: report of 2 cases and review of the literature.勒米尔综合征的演变:2例报告并文献复习
Medicine (Baltimore). 2002 Nov;81(6):458-65. doi: 10.1097/00005792-200211000-00006.