甲状腺自身免疫、抑郁症和双相情感障碍之间的联系。
The Link between Thyroid Autoimmunity, Depression and Bipolar Disorder.
作者信息
Jucevičiūtė Neringa, Žilaitienė Birutė, Aniulienė Rosita, Vanagienė Virginija
机构信息
Faculty of Medicine, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Institute of Endocrinology and Department of Endocrinology, Lithuanian University of Health Sciences, Kaunas, Lithuania.
出版信息
Open Med (Wars). 2019 Jan 16;14:52-58. doi: 10.1515/med-2019-0008. eCollection 2019.
Abstract
Depression and bipolar disorder are two major psychiatric illnesses whose pathophysiology remains elusive. Newly emerging data support the hypothesis that the dysfunction of the immune system might be a potential factor contributing to the development of these mental disorders. The most common organ affected by autoimmunity is the thyroid; therefore, the link between autoimmune thyroid disorders and mental illnesses has been studied since the 1930s. The aim of this review is to discuss the associations between thyroid autoimmunity, depression and bipolar disorder.
摘要
抑郁症和双相情感障碍是两种主要的精神疾病，其病理生理学仍不清楚。新出现的数据支持这样一种假说，即免疫系统功能障碍可能是导致这些精神障碍发生的一个潜在因素。受自身免疫影响最常见的器官是甲状腺；因此，自20世纪30年代以来，人们一直在研究自身免疫性甲状腺疾病与精神疾病之间的联系。这篇综述的目的是讨论甲状腺自身免疫、抑郁症和双相情感障碍之间的关联。
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