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2型糖尿病与骨脆性:特别关注骨成像

Type 2 diabetes mellitus and bone fragility: Special focus on bone imaging.

作者信息

Choi Yong Jun, Chung Yoon-Sok

机构信息

Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, South Korea.

出版信息

Osteoporos Sarcopenia. 2016 Mar;2(1):20-24. doi: 10.1016/j.afos.2016.02.001. Epub 2016 Mar 3.

DOI:10.1016/j.afos.2016.02.001
PMID:30775463
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6372751/
Abstract

Fragility fracture rate is increased in type 2 diabetes patients despite of higher bone mineral density than non-diabetes control subjects. Vertebral fractures are usually asymptomatic; therefore, morphometric radiologic evaluation should be considered especially for diabetes patients. Bone quality may more contribute to the increased risk of osteoporotic fractures in patients with type 2 diabetes than bone mass. Hip geometry, cortical porosity, and trabecular bone score have been studied as bone quality parameters by imaging in type 2 diabetes mellitus.

摘要

尽管2型糖尿病患者的骨矿物质密度高于非糖尿病对照受试者,但其脆性骨折发生率仍有所增加。椎体骨折通常无症状;因此,尤其对于糖尿病患者,应考虑进行形态计量学放射学评估。与骨量相比,骨质量可能对2型糖尿病患者骨质疏松性骨折风险增加的影响更大。通过影像学检查,髋部几何形态、皮质骨孔隙率和小梁骨评分已作为2型糖尿病患者的骨质量参数进行了研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2e7/6372751/88c7e9dcc32b/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2e7/6372751/853b598aa611/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2e7/6372751/c9bc5411f9ff/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2e7/6372751/adaf000565c7/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2e7/6372751/88c7e9dcc32b/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2e7/6372751/853b598aa611/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2e7/6372751/c9bc5411f9ff/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2e7/6372751/adaf000565c7/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2e7/6372751/88c7e9dcc32b/gr4.jpg

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Fracture Risk Prediction by Non-BMD DXA Measures: the 2015 ISCD Official Positions Part 2: Trabecular Bone Score.基于非骨密度双能X线吸收法测量的骨折风险预测:2015年国际临床骨密度学会官方立场 第2部分:小梁骨评分
J Clin Densitom. 2015 Jul-Sep;18(3):309-30. doi: 10.1016/j.jocd.2015.06.008.
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J Diabetes Metab Disord. 2019 Mar 9;18(1):99-106. doi: 10.1007/s40200-019-00395-1. eCollection 2019 Jun.
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