Choi Yong Jun, Chung Yoon-Sok
Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, South Korea.
Osteoporos Sarcopenia. 2016 Mar;2(1):20-24. doi: 10.1016/j.afos.2016.02.001. Epub 2016 Mar 3.
Fragility fracture rate is increased in type 2 diabetes patients despite of higher bone mineral density than non-diabetes control subjects. Vertebral fractures are usually asymptomatic; therefore, morphometric radiologic evaluation should be considered especially for diabetes patients. Bone quality may more contribute to the increased risk of osteoporotic fractures in patients with type 2 diabetes than bone mass. Hip geometry, cortical porosity, and trabecular bone score have been studied as bone quality parameters by imaging in type 2 diabetes mellitus.
尽管2型糖尿病患者的骨矿物质密度高于非糖尿病对照受试者,但其脆性骨折发生率仍有所增加。椎体骨折通常无症状;因此,尤其对于糖尿病患者,应考虑进行形态计量学放射学评估。与骨量相比,骨质量可能对2型糖尿病患者骨质疏松性骨折风险增加的影响更大。通过影像学检查,髋部几何形态、皮质骨孔隙率和小梁骨评分已作为2型糖尿病患者的骨质量参数进行了研究。