Loner Carly A, Crane Peter W
University of Rochester Medical Center, Department of Emergency Medicine, Rochester, New York.
Clin Pract Cases Emerg Med. 2019 Jan 4;3(1):47-50. doi: 10.5811/cpcem.2018.11.40569. eCollection 2019 Feb.
We report a case of acute necrotizing eosinophilic myocarditis (ANEM) secondary to drug rash with eosinophilia and systemic symptoms (DRESS) related to administration of minocycline. Myocarditis is a rare complication of DRESS and can manifest as either a self-limited hypersensitivity myocarditis or as the frequently fatal ANEM. Due to the high morbidity and mortality caused by this disease, emergency physicians should be aware of the potential of ANEM in patients with history of DRESS and new-onset cardiac dysfunction. This case reviews the clinical presentation and management of ANEM and the potential role of extracorporeal membrane oxygenation use in the emergency department.
我们报告了一例继发于与米诺环素给药相关的药物性皮疹伴嗜酸性粒细胞增多和全身症状(DRESS)的急性坏死性嗜酸性粒细胞性心肌炎(ANEM)病例。心肌炎是DRESS的一种罕见并发症,可表现为自限性超敏性心肌炎或常为致命性的ANEM。由于该疾病导致的高发病率和死亡率,急诊医生应意识到有DRESS病史且新发心脏功能障碍患者发生ANEM的可能性。本病例回顾了ANEM的临床表现、治疗以及体外膜肺氧合在急诊科应用的潜在作用。