健康足月婴儿 6 月龄时体脂肪量的人体测量学和临床相关性。
Anthropometric and clinical correlates of fat mass in healthy term infants at 6 months of age.
机构信息
Nutrition and Bioprogramming Department, Instituto Nacional de Perinatología "Isidro Espinosa de los Reyes", Montes Urales 800, Col. Lomas de Virreyes, 11000, Ciudad de México, CP, Mexico.
General Director, Instituto Nacional de Perinatología "Isidro Espinosa de los Reyes", Montes Urales 800, Col. Lomas de Virreyes, 11000, Ciudad de México, CP, Mexico.
出版信息
BMC Pediatr. 2019 Feb 18;19(1):60. doi: 10.1186/s12887-019-1430-x.
BACKGROUND
Body composition in infancy plays a central role in the programming of metabolic diseases. Fat mass (FM) is determined by personal and environmental factors. Anthropometric measurements allow for estimations of FM in many age groups; however, correlations of these measurements with FM in early stages of life are scarcely reported. The aim of this study was to evaluate anthropometric and clinical correlates of FM in healthy term infants at 6 months of age.
METHODS
Healthy term newborns (n = 102) from a prospective cohort. Weight, length, skinfolds (biceps, triceps, subscapular and the sum -SFS-) and waist circumference (WC) were measured at 6 months. Body mass index (BMI) and WC/length ratio were computed. Type of feeding during the first 6 months of age was recorded. Air displacement plethysmography was used to asses FM (percentage -%-) and FM index (FMI) was calculated. Correlations and general linear models were performed to evaluate associations.
RESULTS
Significant correlations were observed between all anthropometric measurements and FM (% and index)(p < 0.001). Exclusive/predominant breastfed infants had higher FM and anthropometric measurements at 6 months. Models that showed the strongest associations with FM (% and index) were SFS + WC + sex + type of feeding.
CONCLUSIONS
Anthropometry showed good correlations with FM at 6 months of age. Skinfolds sum and waist circumference were the strongest anthropometric variables associated to FM. Exclusive/predominant breastfeeding was strongly associated with FM.
背景
婴儿期的身体成分在代谢性疾病的发生发展中起着核心作用。体脂肪量（FM）由个体和环境因素决定。人体测量学测量可用于估算许多年龄段的 FM；然而，这些测量值与生命早期 FM 的相关性鲜有报道。本研究旨在评估健康足月婴儿 6 个月时 FM 的人体测量学和临床相关性。
方法
这是一项前瞻性队列研究中的 102 例健康足月新生儿。在 6 个月时测量体重、身高、皮褶厚度（肱二头肌、肱三头肌、肩胛下和总和-SFS-）和腰围（WC）。计算体重指数（BMI）和 WC/长度比。记录婴儿在出生后前 6 个月的喂养方式。使用空气置换体积描记法评估 FM（%）并计算 FM 指数（FMI）。进行相关性和一般线性模型分析以评估相关性。
结果
所有人体测量学测量值与 FM（%和指数）均呈显著相关性（p<0.001）。纯母乳喂养/主要母乳喂养的婴儿在 6 个月时的 FM 和人体测量值更高。与 FM（%和指数）相关性最强的模型是 SFS+WC+性别+喂养方式。
结论
人体测量学与 6 个月时的 FM 具有良好的相关性。皮褶厚度总和和腰围是与 FM 相关性最强的人体测量学变量。纯母乳喂养/主要母乳喂养与 FM 密切相关。
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