Department of Internal Medicine, All India Institute of Medical Sciences, New Delhi, India.
Indian J Med Res. 2018 Dec;148(6):748-751. doi: 10.4103/ijmr.IJMR_888_16.
Narcolepsy is a common sleep disorder in Western countries but rarely reported from India. Here, we report a small case series of four narcolepsy patients seen over a four year period in the sleep clinic of a tertiary care hospital in north India. The diagnosis was established by clinical history and two or more sleep-onset rapid eye movements (SOREMs) on multiple sleep latency tests (MSLTs) following overnight polysomnography (PSG). The mean age of patients was 26.2±6.4 yr; one patient had associated cataplexy and another one had all four cardinal symptoms of narcolepsy. All these patients had a history of excessive daytime sleepiness (EDS). The mean body mass index was 24.2±4.7 kg/m. The mean sleep latency during MSLT was 2.7±1.3 min, and the mean REM latency was 5.7±2.9 min. Narcolepsy, although rarely reported from India, should be suspected in young non-obese patients complaining of EDS and confirmed by performing MSLT following overnight PSG.
嗜睡症是西方国家常见的睡眠障碍，但在印度很少见。在这里，我们报告了在印度北部一家三级医院的睡眠诊所中，四年期间观察到的四例嗜睡症患者的小病例系列。诊断依据是临床病史和多导睡眠图（PSG）后多次睡眠潜伏期试验（MSLT）上的两个或更多睡眠起始快速眼动（SOREMs）。患者的平均年龄为 26.2±6.4 岁；一名患者伴有猝倒，另一名患者具有嗜睡症的所有四个主要症状。所有这些患者都有白天过度嗜睡（EDS）的病史。平均体重指数为 24.2±4.7 kg/m。MSLT 期间的平均睡眠潜伏期为 2.7±1.3 分钟，平均 REM 潜伏期为 5.7±2.9 分钟。嗜睡症虽然在印度很少见，但对于抱怨 EDS 的年轻非肥胖患者应怀疑患有嗜睡症，并通过在整夜 PSG 后进行 MSLT 来确认。
