Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Eur Rev Med Pharmacol Sci. 2019 Feb;23(3):1158-1164. doi: 10.26355/eurrev_201902_17007.
With the introduction of HAART, the life expectancy of the patients infected with HIV almost approached that of the general population. The incidence of certain HIV-Associated cancers as Kaposi Sarcoma (KS) and Non-Hodgkin Lymphoma (NHL) decreased, while an increase in Non-AIDS-Defining cancers (NADCs) has been documented. HIV infection is a risk factor for numerous cancers in PLWH. Breast cancer is the most common cancer worldwide among all women. The association between HIV infection and breast cancer has not been thoroughly investigated: when compared to the general population, people living with HIV/AIDS (PLWHA) have a similar or slightly lower risk of breast cancer. Screening tests are essential weapons to fight cancer burden and more effective therapeutic and preventive strategies are needed, especially among PLWHA. Further and more comprehensive studies are needed to better characterize breast cancer among PLWH.
随着高效抗逆转录病毒治疗(HAART)的引入,感染 HIV 的患者的预期寿命几乎接近普通人群。某些与 HIV 相关的癌症(如卡波西肉瘤(KS)和非霍奇金淋巴瘤(NHL))的发病率有所下降,而非艾滋病定义性癌症(NADCs)的发病率却有所上升。HIV 感染是 PLWH 中许多癌症的危险因素。乳腺癌是全世界所有女性中最常见的癌症。HIV 感染与乳腺癌之间的关系尚未得到彻底研究:与普通人群相比,HIV 感染者/艾滋病患者(PLWHA)患乳腺癌的风险相似或略低。筛查测试是对抗癌症负担的重要武器,需要更有效的治疗和预防策略,尤其是在 PLWHA 中。需要进一步进行更全面的研究,以更好地了解 PLWH 中的乳腺癌。