Centro de Investigaciones Químicas, IICBA, Universidad Autónoma del Estado de Morelos, Cuernavaca, Mexico.
Magn Reson Chem. 2019 Dec;57(12):994-1070. doi: 10.1002/mrc.4857. Epub 2019 Jun 5.
Alkamides are the major and characteristic chemical compounds of the plants belonging to the Piper genus. These compounds are responsible for the flavor of pepper spices and for its broad use in cuisine across many regions of the world. Humans are in contact every day with these substances, which additionally show a broad variety of pharmacological activities, making them an important research target. A large amount of NMR data for these natural products is dispersed throughout literature. Its organization will help those research groups interested in their identification and structural elucidation. This review summarizes the H and C NMR data of 268 Piper amides in a systematic and orderly way, with a discussion on their biological activities, biosynthetic aspects, and NMR analysis of typical and relevant aspects of this information.
酰胺类化合物是胡椒属植物的主要特征性化学物质。这些化合物赋予了辣椒香料的味道，使其在世界许多地区的烹饪中得到广泛应用。人类每天都与这些物质接触，它们还表现出广泛的药理活性，这使它们成为一个重要的研究目标。大量关于这些天然产物的 NMR 数据分散在文献中。对这些数据进行组织将有助于那些对其鉴定和结构阐明感兴趣的研究小组。本综述以系统有序的方式总结了 268 种胡椒酰胺的 H 和 C NMR 数据，并讨论了它们的生物活性、生物合成方面以及该信息的典型和相关方面的 NMR 分析。
