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[蠕形螨寄生虫与慢性睑缘炎]

[DEMODEX PARASITES AND CHRONIC BLEPHARITIS].

作者信息

Lavy Itay

机构信息

Department of Ophthalmology, Hadassah Medical Center, Jerusalem, Israel.

Faculty of Medicine, The Hebrew University, Jerusalem, Israel.

出版信息

Harefuah. 2019 Feb;158(2):112-114.

Abstract

In the current issue of 'Harefuah', Livny et al present an article on the prevalence of Demodex parasites in patients with chronic blepharitis and healthy controls in Israel. This prospective case controlled study describes the quantitative connection between the number of parasites found on 6-8 sample eyelashes and chronic blepharitis, one of the most prevalent conditions in the general population and especially prevalent in the ophthalmologist office visits. Blepharitis symptoms may vary from being asymptomatic, chronic condition, dry eye, and sometimes even a severe compromise of ocular surface with a morbid impact on patient quality of life. In recent decades, progress was presented in a number of published articles including one meta-analysis that connects blepharitis with Demodex and the treatment of both with tea tree oil. Also, two different species of Demodex were identified which prefer to inhabit different areas of the eyelid. While the presented data do indicate a quantitative connection between Demodex and blepharitis, questions are raised as to whether there is a causative relationship between them? Can Demodex cause chronic blepharitis as an only factor? Or a symbiotic parasite which proliferate in blepharitis by consuming the debris and byproducts of blepharitis? Is it both? Although many theories exist, the answer is yet to be proven, but the consensus today is to combine anti-Demodex products while treating refractory chronic blepharitis.

摘要

在本期《Harefuah》杂志中,利夫尼等人发表了一篇关于以色列慢性睑缘炎患者和健康对照者中蠕形螨寄生虫患病率的文章。这项前瞻性病例对照研究描述了在6 - 8根样本睫毛上发现的寄生虫数量与慢性睑缘炎之间的定量关系,慢性睑缘炎是普通人群中最常见的病症之一,在眼科门诊就诊患者中尤为普遍。睑缘炎的症状可能各不相同,有无症状的慢性情况、干眼,有时甚至会严重损害眼表,对患者生活质量产生不良影响。近几十年来,许多已发表的文章都取得了进展,其中包括一项将睑缘炎与蠕形螨以及两者用茶树油治疗联系起来的荟萃分析。此外,还鉴定出了两种不同的蠕形螨,它们更喜欢栖息在眼睑的不同部位。虽然所呈现的数据确实表明了蠕形螨与睑缘炎之间的定量关系,但人们提出了疑问:它们之间是否存在因果关系?蠕形螨能否作为唯一因素导致慢性睑缘炎?还是一种共生寄生虫,通过消耗睑缘炎的碎屑和副产品在睑缘炎中增殖?是两者皆是吗?尽管存在许多理论,但答案尚未得到证实,但如今的共识是在治疗难治性慢性睑缘炎时联合使用抗蠕形螨产品。

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