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糖尿病与斋月:阿尔及利亚人群中的一项多中心研究。

Diabetes and Ramadan: A multicenter study in Algerian population.

机构信息

Department of Internal Medicine, Setif University Hospital, Algeria.

Department of Internal Medicine, Setif University Hospital, Algeria.

出版信息

Diabetes Res Clin Pract. 2019 Apr;150:322-330. doi: 10.1016/j.diabres.2019.02.008. Epub 2019 Feb 16.

Abstract

OBJECTIVE

The aims of this study are to describe the behaviour of an Algerian population with diabetes and the consequences of fasting.

METHODS

In 2017, a prospective multicenter study was conducted in 26 counties before and after fasting. The study concerned 901 patients with 836 type 2 diabetes mellitus (T2DM) and 65 with type 1 diabetes mellitus (T1DM).

RESULTS

The average age for T2DM and T1DM was 57.86 ± 10.44 and 45.8 ± 17.69 years respectively. The duration of diabetes was 9.09 ± 8.19 for T1DM and 7.87 ± 5.97 years for T2DM. 89.1% of T2DM and 69.2% of T1DM fasted during Ramadan. 51.4% of T2DM were classified among the high and very high risk. The average glycemia increased (162 ± 49 mg/dL vs. 197 ± 65 mg/dl) (p 0.035 × 10)]. About 30% of patients had hypoglycemic episodes. Self-monitoring blood glucose (SMBG) during Ramadan was not conform to the physicians' advice and thus significantly lowered than suggested (2.6 vs. 3.4 per day). The therapeutic adjustment was mainly a reduction in insulin dose and glucose-lowering agents.

CONCLUSION

Diabetic patients insist on fasting regardless of their doctors' warnings. The main consequences were hyperglycemia and hypoglycemia. SMBG was less checked during Ramadan. Therapeutic education remains unsufficient and needs much more emphasis.

摘要

目的

本研究旨在描述阿尔及利亚糖尿病患者的行为及其禁食的后果。

方法

2017 年,在禁食前后进行了一项前瞻性多中心研究,涉及 901 例 2 型糖尿病(T2DM)和 65 例 1 型糖尿病(T1DM)患者。

结果

T2DM 和 T1DM 的平均年龄分别为 57.86±10.44 岁和 45.8±17.69 岁。T1DM 和 T2DM 的糖尿病病程分别为 9.09±8.19 年和 7.87±5.97 年。89.1%的 T2DM 和 69.2%的 T1DM 在斋月期间禁食。51.4%的 T2DM 患者被归类为高风险和极高风险。平均血糖升高(162±49mg/dL 与 197±65mg/dl)(p<0.035×10)。约 30%的患者发生低血糖事件。斋月期间自我监测血糖(SMBG)不符合医生建议,明显低于建议值(每天 2.6 次与 3.4 次)。治疗调整主要是减少胰岛素剂量和降血糖药物。

结论

糖尿病患者不顾医生的警告坚持禁食。主要后果是高血糖和低血糖。斋月期间 SMBG 检查较少。治疗教育仍然不足,需要更多的重视。

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