Department of Otorhinolaryngology - Head and Neck Surgery, Alder Hey Children's Hospital, Liverpool, UK.
Clin Otolaryngol. 2019 May;44(3):366-371. doi: 10.1111/coa.13315. Epub 2019 Mar 25.
Surgical drainage is the traditional mainstay of treatment of paediatric deep neck space infection (DNSI), but recently non-operative management in selected cases has been advocated. We sought to identify any characteristics predictive of requirement for surgical intervention.
Retrospective cohort study using receiver operating characteristics analyses.
Tertiary referral paediatric hospital.
Children (≤16 years) with a radiologically confirmed diagnosis of retro- or parapharyngeal abscess over a ten-year period.
Predictive value of clinical and radiological variables in determining the requirement for surgical intervention. Length of hospital stay (LoS) was also examined.
Ninety-three children were studied, 15 (16.1%) of whom underwent immediate surgery, 42 (45.2%) of whom underwent delayed surgery following an initial period of conservative management, and 36 (38.7%) of whom were managed conservatively. Age, WCC and CRP were not predictive of the need for surgical drainage. Radiological abscess diameter, however, was predictive of requirement surgery (AUC = 0.85 [95% CI ± 0.09] P = 0.02), with a cut-off value of 2.5 cm determined assuming equal weight to sensitivity and specificity. All DNSIs were successfully treated with no adverse outcomes, and there was no significant difference in LoS between groups. In those managed surgically, outcome and LoS did not depend on yield of pus.
Selected paediatric DNSIs can be successfully managed conservatively, with abscess diameter >2.5 cm a significant predictor of need for surgical intervention. Any benefit of surgery does not appear to depend on intra-operative yield of pus.
手术引流是治疗小儿咽后和咽旁间隙感染(DNSI)的传统主要方法,但最近在某些病例中提倡采用非手术治疗。我们试图确定任何预测需要手术干预的特征。
使用接受者操作特征分析的回顾性队列研究。
三级转诊儿科医院。
在十年期间,经影像学证实患有咽后或咽旁脓肿的儿童(≤16 岁)。
临床和影像学变量预测需要手术干预的价值。还检查了住院时间(LoS)。
研究了 93 名儿童,其中 15 名(16.1%)立即接受了手术,42 名(45.2%)在接受了初始保守治疗后接受了延迟手术,36 名(38.7%)接受了保守治疗。年龄、WCC 和 CRP 不能预测是否需要手术引流。然而,影像学脓肿直径是预测手术需求的因素(AUC=0.85[95%CI±0.09]P=0.02),假设灵敏度和特异性权重相等,确定了 2.5cm 的截止值。所有 DNSI 均成功治疗,无不良结局,且各组之间的 LOS 无显著差异。在接受手术治疗的患者中,结局和 LOS 与脓液产量无关。
选择的小儿 DNSI 可以成功地保守治疗,脓肿直径>2.5cm 是需要手术干预的显著预测因素。手术的任何益处似乎都不取决于术中脓液产量。