（紫堇科紫堇属）叶和干皮的化学成分。
Chemical constituents from leaves and trunk bark of (Violaceae).
机构信息
Department of Organic Chemistry, Faculty of Science, University of Yaounde I, Yaounde, Cameroon.
Department of Biochemistry, Faculty of Science, University of Yaounde I, Yaounde, Cameroon.
出版信息
Nat Prod Res. 2020 Jul;34(14):2014-2021. doi: 10.1080/14786419.2019.1573230. Epub 2019 Feb 20.
Two new coruleoellagic acid derivatives, 3,4',5,5',-tetramethylcoruleoellagic acid ; 3',4,4',5,5'-pentamethylcoruleoellagic acid and a new friedelane-type triterpene derivative rinol , were isolated from leaves and trunk bark of (Violaceae) along with seven known compounds including 3,3',4,4',5'-pentamethylcoruleoellagic acid , hexamethylcoruleoellagic acid 28-hydroxyfriedelin friedelin friedelan-3-ol scopoletin and β-sitosterol-3--β-D-glucopyranoside Their structures were elucidated by means of spectroscopic methods including IR, 1D and 2D NMR in conjunction with mass spectrometry. Crude extracts of leaves and trunk bark as well as compounds were evaluated for their antibacterial activities against 7 pathogenic bacterial strains ( ATCC49619, ATCC 43300, ATCC 700603, ATCC 49247, ATCC 25922, HM601, BAA 977). Compound displayed noteworthy activity against with MIC value of 9.38 µg/mL.
从（堇菜科）的叶子和干树皮中分离得到了两种新的柯罗瑞酸衍生物，3,4',5,5'-四甲基柯罗瑞酸；3',4,4',5,5'-五甲基柯罗瑞酸和一种新的弗里德烷型三萜衍生物rinol，以及 7 种已知化合物，包括 3,3',4,4',5'-五甲基柯罗瑞酸、六甲基柯罗瑞酸、28-羟基弗里德醇、弗里德醇、弗里德兰-3-醇、山柰酚和β-谷甾醇-3-O-β-D-吡喃葡萄糖苷。通过光谱方法，包括红外、1D 和 2D NMR 以及质谱，阐明了它们的结构。对叶子和干树皮的粗提取物以及化合物进行了评估，以测试它们对 7 种致病性细菌菌株（ATCC49619、ATCC 43300、ATCC 700603、ATCC 49247、ATCC 25922、HM601、BAA 977）的抗菌活性。化合物对具有 MIC 值为 9.38 μg/mL 的显著活性。
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