Vavolizza Rick D, Grabski David F, Levin Daniel E, Gander Jeffrey W
University of Virginia School of Medicine, Charlottesville, Virginia.
Department of Surgery, University of Virginia School of Medicine, Charlottesville, Virginia.
Pediatr Transplant. 2019 May;23(3):e13374. doi: 10.1111/petr.13374. Epub 2019 Feb 20.
Gastrostomy tube (GT) placement is a common pediatric surgical procedure typically indicated for oral aversion. This may develop in patients with congenital heart disease (CHD) who require an orthotopic heart transplant (OHT). The safety profile of GT placement in OHT patients who are immunosuppressed is unknown. Given the potential increased risk of wound site complications on a patient receiving immunosuppression, we sought to determine the safety profile of GT placement in pediatric patients with OHT.
We performed a retrospective case series of all pediatric OHT recipients who subsequently underwent GT placement from January 1, 2009, to August 1, 2018, at the University of Virginia Children's Hospital. Major GT complications of wound breakdown, wound infection, peristomal GT leakage, ileus, or persistent emesis, and minor GT complication including the presence of granulation tissue are reported.
Six patients who had a pediatric OHT subsequently underwent GT placement over the study period. There were no major 30-day or 90-day GT complications. One patient had excessive granulation tissue at their GT site. There were no accounts of acute kidney injury, urinary tract infection, sepsis, or pneumonia.
Gastrostomy tube (GT) placement appears to be safe in pediatric OHT patients who are on immunosuppressive medications and unable to feed orally. This is the first study documenting the safety profile of GTs in pediatric OHT patients and may aid clinicians to make decisions regarding this intervention.
胃造口管(GT)置入是一种常见的儿科外科手术,通常用于口腔厌恶症患者。这可能发生在需要原位心脏移植(OHT)的先天性心脏病(CHD)患者中。免疫抑制的OHT患者进行GT置入的安全性尚不清楚。鉴于免疫抑制患者伤口部位并发症的潜在风险增加,我们试图确定儿科OHT患者GT置入的安全性。
我们对2009年1月1日至2018年8月1日在弗吉尼亚大学儿童医院随后接受GT置入的所有儿科OHT受者进行了回顾性病例系列研究。报告了GT的主要并发症,包括伤口破裂、伤口感染、造口周围GT渗漏、肠梗阻或持续性呕吐,以及GT的次要并发症,包括肉芽组织的存在。
在研究期间,6例儿科OHT患者随后接受了GT置入。没有发生30天或90天的主要GT并发症。1例患者的GT部位有过多的肉芽组织。没有急性肾损伤、尿路感染、败血症或肺炎的报告。
对于正在接受免疫抑制药物治疗且无法经口进食的儿科OHT患者,胃造口管(GT)置入似乎是安全的。这是第一项记录儿科OHT患者GT安全性的研究,可能有助于临床医生做出关于这种干预措施的决策。