University Hospital Tuebingen, Department of Psychosomatic Medicine and Psychotherapy, Osianderstr. 5, 72076, Tuebingen, Germany.
University Hospital Tuebingen, Department of Sports Medicine, Hoppe-Seyler-Str. 6, 72076, Tuebingen, Germany.
Sci Rep. 2019 Feb 20;9(1):2381. doi: 10.1038/s41598-019-38828-9.
The performance enhancing (ergogenic) placebo effect is elicited by an inert treatment and caused by positive affective appraisal of effort perception. Frontal alpha asymmetry (FAA) is a neurobiological correlate of positive affect. This study investigates, whether receiving an ergogenic placebo increases FAA and whether scores on the behavioral inhibition and activation system (BIS/BAS) scales affect this increase in FAA. Nineteen competitive male cyclists (37.26 ± 9.82 years) performed two maximum effort time trials. The first served as baseline for the second intervention time trial, where athletes received a placebo ergogenic aid or no treatment. We recorded FAA using EEG throughout all time trials and assessed BIS/BAS by questionnaire. There was a significant difference in change from baseline to intervention time trial in FAA during cycling in response to the placebo ergogenic aid compared to the control group. BIS, the BAS subscale Drive and the BAS-BIS difference score significantly co-varied with the change in FAA from baseline to intervention time trial in response to the placebo ergogenic aid. Administering a placebo ergogenic aid significantly influenced FAA during maximum effort cycling. Those athletes with a more pronounced goal seeking persistence and an overall dominance of the BAS over the BIS showed a significantly greater increase in FAA in response to a placebo ergogenic aid. A more pronounced BIS, however, seems to antagonize the increase in FAA associated with the ergogenic placebo response.
增强表现（促进表现）的安慰剂效应是由惰性治疗引起的，是对努力感知的积极情感评估的结果。额区阿尔法不对称（FAA）是积极情绪的神经生物学相关物。本研究旨在探讨接受促进表现的安慰剂是否会增加 FAA，以及行为抑制和激活系统（BIS/BAS）量表的得分是否会影响 FAA 的增加。19 名有竞争力的男性自行车运动员（37.26±9.82 岁）进行了两次最大努力计时赛。第一次作为第二次干预计时赛的基线，运动员接受了促进表现的安慰剂或无治疗。我们在整个计时赛中使用 EEG 记录 FAA，并通过问卷评估 BIS/BAS。与对照组相比，在接受促进表现的安慰剂时，在自行车运动中 FAA 从基线到干预计时赛的变化有显著差异。BIS、BAS 亚量表驱动和 BAS-BIS 差异评分与 FAA 从基线到干预计时赛的变化显著相关。给予促进表现的安慰剂显著影响了最大努力骑行时的 FAA。那些表现出更明显的目标追求坚持和 BAS 总体上优于 BIS 的运动员，在接受促进表现的安慰剂时，FAA 的增加幅度显著更大。然而，更明显的 BIS 似乎会拮抗与促进表现的安慰剂反应相关的 FAA 增加。
