Landi Alessandro, Grasso Giovanni, Mancarella Cristina, Dugoni Demo Eugenio, Gregori Fabrizio, Iacopino Giorgia, Bai Harrison Xiao, Marotta Nicola, Iaquinandi Andrea, Delfini Roberto
Department of Neurology and Psychiatry, Division of Neurosurgery, "Sapienza" University of Rome, Rome, Italy.
Department of Experimental Biomedicine and Clinical Neurosciences, University of Palermo, Palermo, Italy.
J Craniovertebr Junction Spine. 2018 Oct-Dec;9(4):260-266. doi: 10.4103/jcvjs.JCVJS_94_18.
The recurrence of a lumbar disc herniation (LDH) is a common cause of poor outcome following lumbar discectomy. The aim of this study was to assess a potential relationship between the incidence of recurrent LDH and the surgical technique used. Furthermore, we tried to define the best surgical technique for the treatment of recurrent LDH to limit subsequent recurrences.
A retrospective study was conducted on 979 consecutive patients treated for LDH. A multivariate analysis tried to identify a possible correlation between (1) the surgical technique used to treat the primary LDH and its recurrence; (2) technique used to treat the recurrence of LDH and the second recurrence; and (3) incidence of recurrence and clinical outcome. Data were analyzed with the Pearson's Chi-square test for its significance.
In 582 cases (59.4%), a discectomy was performed, while in 381 (40.6%), a herniectomy was undertaken. In 16 cases, a procedure marked as "other" was performed. Among all patients, 110 (11.2%) had a recurrence. Recurrent LDH was observed in 55 patients following discectomy (9.45%), in 45 following herniectomy (11.8%), and in 10 (62.5%) following other surgery. Our data showed that 90.5% of discectomies and 88.2% of the herniectomies had a good clinical outcome, whereas other surgeries presented a recurrence rate of 62.5% (Pearson's χ< 0.001). No statistical differences were observed between discectomy or herniectomy, for the treatment of the recurrence, and the incidence for the second recurrences ( > 0.05). A significant statistical correlation emerged between the use of other techniques and the incidence for the second recurrences ( < 0.05).
The recurrence of an LDH is one of the most feared complications following surgery. Although the standard discectomy has been considered more protective toward the recurrence compared to herniectomy, our data suggest that there is no significant correlation between the surgical technique and the risk of LDH recurrence.
腰椎间盘突出症(LDH)复发是腰椎间盘切除术后预后不良的常见原因。本研究旨在评估复发性LDH的发生率与所采用手术技术之间的潜在关系。此外,我们试图确定治疗复发性LDH以限制后续复发的最佳手术技术。
对979例连续接受LDH治疗的患者进行回顾性研究。多因素分析试图确定(1)用于治疗原发性LDH的手术技术与其复发之间的可能相关性;(2)用于治疗LDH复发和第二次复发的技术;以及(3)复发发生率与临床结果之间的关系。采用Pearson卡方检验分析数据的显著性。
582例(59.4%)患者接受了椎间盘切除术,381例(40.6%)患者接受了疝切除术。16例患者进行了标记为“其他”的手术。所有患者中,110例(11.2%)出现复发。椎间盘切除术后55例患者(9.45%)出现复发性LDH,疝切除术后45例(11.8%),其他手术后10例(62.5%)。我们的数据显示,90.5%的椎间盘切除术和88.2%的疝切除术临床效果良好,而其他手术的复发率为62.5%(Pearson χ<0.001)。在治疗复发方面,椎间盘切除术或疝切除术与第二次复发的发生率之间未观察到统计学差异(>0.05)。其他技术的使用与第二次复发的发生率之间出现了显著的统计学相关性(<0.05)。
LDH复发是手术后最令人担忧的并发症之一。尽管与疝切除术相比,标准的椎间盘切除术被认为对复发更具保护作用,但我们的数据表明,手术技术与LDH复发风险之间没有显著相关性。